COMPARISON OF MYCOBACTERIUM TUBERCULOSIS BEIJING GENOTYPE WITH OTHER MYCOBACTERIUM TUBERCULOSIS STRAINS USING MIRU-VNTR METHOD

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MOZAFARI M.; FARNIA P.; JAFARIAN M.; RAZAVI DELIGANI M.R.; KAZEMPOUR M.; MASJEDI M.R.; VELAYATI A.A.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: IRANIAN SOUTH MEDICAL JOURNAL (ISMJ) Year:2012 | Volume:15 | Issue:1 Page(s): 1-12

Download Full-Text

Persian Verion

View:

980

Download:

Cites:

Information Journal Paper

Title

COMPARISON OF MYCOBACTERIUM TUBERCULOSIS BEIJING GENOTYPE WITH OTHER MYCOBACTERIUM TUBERCULOSIS STRAINS USING MIRU-VNTR METHOD

Author(s)

Keywords

MIRU-VNTRQ2

MYCOBACTERIUM TUBERCULOSISQ2

BEIJING GENOTYPEQ3

TUBERCULOSISQ3

Abstract

Background: Recently it is shown that TUBERCULOSIS/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank"> MYCOBACTERIUM TUBERCULOSIS BEIJING GENOTYPE are associated with drug resistance. Thus a simple and rapid method is required for identification and differentiation of Beijing family isolates. Therefore the aim of this study is to evaluate discriminatory power of different loci in both 12 MIRU-VNTR and 15 MIRU-VNTR Methods for BEIJING GENOTYPE.Methods: In total 105 TUBERCULOSIS/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank"> MYCOBACTERIUM TUBERCULOSIS strains were identified by spoligotyping, then genomic analysis was carried out by using 12 and 15 MIRU-VNTR methods. Allelic diversity for each locus was calculated using Hunter Gaston Discriminatory Index (HGI).Results: With spoligotyping 20 out of 105 isolates (19.05%) belonged to the Beijing family. Investigating all strains with 12 and 15 MIRU-VNTR showed that 11 loci were highly discriminative (HGI ³0.6) and QUB26 had the highest discriminatory power (HGI=0.84). Number of repeats in QUB11b was specific for BEIJING GENOTYPE, and only MIRU16 was highly discriminator for this genotype. QUB26, Mtub21, MIRU39, MIRU27, MIRU23 and MIRU26 were moderately discriminator (0.4£HGI<0.6) and other loci were poorly discriminator for Beijing strains (HGI<0.4).Conclusion: 12 and 15 locus MIRU-VNTR are simple and rapid methods and suitable for differentiation of BEIJING GENOTYPE from other MTB strains, however these two methods are not suitable for discriminating Beijing family among themselves. In overall discriminatory power of 15 locus MIRU-VNTR method was higher than 12 locus MIRU-VNTR.

Cites

EVALUATION OF CONSERVATION IN CARD SEQUENCE’S GENE AND ITS APPLICATION IN RAPID DETECTION OF MYCOBACTERIUM TUBERCULOSIS

References

No record.

Cite

APA: Copy

MOZAFARI, M., FARNIA, P., JAFARIAN, M., RAZAVI DELIGANI, M.R., KAZEMPOUR, M., MASJEDI, M.R., & VELAYATI, A.A.. (2012). COMPARISON OF MYCOBACTERIUM TUBERCULOSIS BEIJING GENOTYPE WITH OTHER MYCOBACTERIUM TUBERCULOSIS STRAINS USING MIRU-VNTR METHOD. IRANIAN SOUTH MEDICAL JOURNAL (ISMJ), 15(1), 1-12. SID. https://sid.ir/paper/33994/en

Vancouver: Copy

MOZAFARI M., FARNIA P., JAFARIAN M., RAZAVI DELIGANI M.R., KAZEMPOUR M., MASJEDI M.R., VELAYATI A.A.. COMPARISON OF MYCOBACTERIUM TUBERCULOSIS BEIJING GENOTYPE WITH OTHER MYCOBACTERIUM TUBERCULOSIS STRAINS USING MIRU-VNTR METHOD. IRANIAN SOUTH MEDICAL JOURNAL (ISMJ)[Internet]. 2012;15(1):1-12. Available from: https://sid.ir/paper/33994/en

IEEE: Copy

M. MOZAFARI, P. FARNIA, M. JAFARIAN, M.R. RAZAVI DELIGANI, M. KAZEMPOUR, M.R. MASJEDI, and A.A. VELAYATI, “COMPARISON OF MYCOBACTERIUM TUBERCULOSIS BEIJING GENOTYPE WITH OTHER MYCOBACTERIUM TUBERCULOSIS STRAINS USING MIRU-VNTR METHOD,” IRANIAN SOUTH MEDICAL JOURNAL (ISMJ), vol. 15, no. 1, pp. 1–12, 2012, [Online]. Available: https://sid.ir/paper/33994/en

Related Journal Papers