مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

301
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

150
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

1

Information Journal Paper

Title

SYNTHESIS, CHARACTERIZATION AND BIOCOMPATIBILITY EVALUATION OF HYDROXYAPATITE - GELATIN POLYLACTIC ACID TERNARY NANOCOMPOSITE

Pages

  127-134

Abstract

 Objective (s): The current study reports the production and BIOCOMPATIBILITY evaluation of a ternary nanocomposite consisting of HA, PLA, and GELATIN for biomedical application.Materials and Methods: HYDROXYAPATITE nanopowder (HA: Ca10 (PO4)6 (OH)2) was produced by burning the bovine cortical bone within the temperature range of 350-450oC followed by heating in an oven at 800. Synthesis of the ternary nanocomposite was carried out in two steps: synthesis of GELATIN-hydroxyapatite binary nanocomposite and addition of poly lactic acid with different percentages to the resulting composition. The crystal structure was determined by Xray diffraction (XRD), while major elements and impurities of HYDROXYAPATITE were identified by elemental analysis of X-ray fluorescence (XRF). Functional groups were determined by Fourier transform infrared spectroscopy (FTIR). Morphology and size of the NANOCOMPOSITES were evaluated using field emission scanning electron microscope (FESEM). BIOCOMPATIBILITY of NANOCOMPOSITES was investigated by MTT assay.Results: XRD patterns verified the ideal crystal structure of the HYDROXYAPATITE, which indicated an appropriate synthesis process and absence of disturbing phases. Results of FTIR analysis determined the polymers’ functional groups, specified formation of the polymers on the HYDROXYAPATITE surface, and verified synthesis of nHA/PLA/Gel composite. FESEM images also indicated the homogeneous structure of the composite in the range of 50 nanometers. MTT assay results confirmed the BIOCOMPATIBILITY of nanocomposite samples.Conclusion: This study suggested that the ternary nanocomposite of nHA/PLA/Gel can be a good candidate for biomedical application such as drug delivery systems, but for evaluation of its potential in hard tissue replacement, mechanical tests should be performed.

Cites

References

  • No record.

    • Cite

    APA: Copy

    NABIPOUR, Z., NOURBAKHSH, M.S., & BANIASADI, M.. (2016). SYNTHESIS, CHARACTERIZATION AND BIOCOMPATIBILITY EVALUATION OF HYDROXYAPATITE - GELATIN POLYLACTIC ACID TERNARY NANOCOMPOSITE. NANOMEDICINE JOURNAL, 3(2), 127-134. SID. https://sid.ir/paper/341575/en

    Vancouver: Copy

    NABIPOUR Z., NOURBAKHSH M.S., BANIASADI M.. SYNTHESIS, CHARACTERIZATION AND BIOCOMPATIBILITY EVALUATION OF HYDROXYAPATITE - GELATIN POLYLACTIC ACID TERNARY NANOCOMPOSITE. NANOMEDICINE JOURNAL[Internet]. 2016;3(2):127-134. Available from: https://sid.ir/paper/341575/en

    IEEE: Copy

    Z. NABIPOUR, M.S. NOURBAKHSH, and M. BANIASADI, “SYNTHESIS, CHARACTERIZATION AND BIOCOMPATIBILITY EVALUATION OF HYDROXYAPATITE - GELATIN POLYLACTIC ACID TERNARY NANOCOMPOSITE,” NANOMEDICINE JOURNAL, vol. 3, no. 2, pp. 127–134, 2016, [Online]. Available: https://sid.ir/paper/341575/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button