STUDY OF PHYSICAL PROPERTIES AND RELEASE PROFILE OF THEOPHILLINE PELLETS PREPARED BY PAN COATING METHOD

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BOLOUR CHIAN N.; ABOU FAZELI R.; HESSAMI E.

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Journal: PHARMACEUTICAL SCIENCES Year:2003 | Volume:- | Issue:1 Page(s): 1-10

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Title

STUDY OF PHYSICAL PROPERTIES AND RELEASE PROFILE OF THEOPHILLINE PELLETS PREPARED BY PAN COATING METHOD

Author(s)

BOLOUR CHIAN N. | ABOU FAZELI R. | HESSAMI E. | Issue Writer Certificate

Keywords

THEOPHYLLINEQ3

PELLETSQ2

PAN COATINGQ3

SUSTAINED RELEASEQ2

Abstract

In this study, THEOPHYLLINE SUSTAINED RELEASE PELLETS were prepared by PAN COATING method using different additives (including PVP, acacia, corn starch, avicel PH 101, dicalcium phosphate, sucrose and HPMC) and Eudragit RS 100 and RL 100. Wet granulation and pelletization techniques were used to prepare the initial cores. After determination of physical properties, the prepared particles were coated using Eudragit solutions. Based on the results of dissolution tests, although cores containing dicalcium phosphate, PVP additives and Eudragit RS 100 as the coating agent, did not show the desirable release pattern, but mixtures of PELLETS with different film thickness, Showed drug release profiles which were comparable with USP criteria.

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APA: Copy

BOLOUR CHIAN, N., ABOU FAZELI, R., & HESSAMI, E.. (2003). STUDY OF PHYSICAL PROPERTIES AND RELEASE PROFILE OF THEOPHILLINE PELLETS PREPARED BY PAN COATING METHOD. PHARMACEUTICAL SCIENCES, -(1), 1-10. SID. https://sid.ir/paper/357749/en

Vancouver: Copy

BOLOUR CHIAN N., ABOU FAZELI R., HESSAMI E.. STUDY OF PHYSICAL PROPERTIES AND RELEASE PROFILE OF THEOPHILLINE PELLETS PREPARED BY PAN COATING METHOD. PHARMACEUTICAL SCIENCES[Internet]. 2003;-(1):1-10. Available from: https://sid.ir/paper/357749/en

IEEE: Copy

N. BOLOUR CHIAN, R. ABOU FAZELI, and E. HESSAMI, “STUDY OF PHYSICAL PROPERTIES AND RELEASE PROFILE OF THEOPHILLINE PELLETS PREPARED BY PAN COATING METHOD,” PHARMACEUTICAL SCIENCES, vol. -, no. 1, pp. 1–10, 2003, [Online]. Available: https://sid.ir/paper/357749/en

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