Antibacterial Activity of Alcoholic and Aqueous Extracts of Various Organs of Citrus medica on 10 Human Pathogenic in Vitro

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Shojaemehr Mohadeseh; Alamholo Mostafa

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Journal: Iranian Journal of Medical Microbiology Year:2019 | Volume:13 | Issue:4 Page(s): 310-320

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Information Journal Paper

Title

Antibacterial Activity of Alcoholic and Aqueous Extracts of Various Organs of Citrus medica on 10 Human Pathogenic in Vitro

Author(s)

Shojaemehr Mohadeseh | Alamholo Mostafa | Issue Writer Certificate

Keywords

Citrus medicaQ1

Secondary metabolitesQ1

antibacterialQ1

Abstract

Background and Aims: Medicinal herbs are used due to fewer side effects for produce of natural drugs in the pharmaceutical industry. The aim of this study was investigation of antibacterial and antioxidant activity of Citrus medica skin extracts against 10 human pathogenic bacterial and investigation of Secondary metabolites in vitro. Materials and Methods: Color and white Skin of Citrus medica under the supervision of Citrus Research Center experts were collected from Ramsar City, Mazandaran Province, Iran in 2014. antibacterial activity by agar well diffusion method, total phenolic content by Folin-Ciocalteu method, total flavonoid by aluminum chloride and antioxidant properties by DPPH method were investigated. Phytochemical investigation of Secondary metabolites was performed. Results & Conclusion: The highest inhibitory activity was observed on methanol extract of color skin on Bacillus cereus bacteria. IC50 methanol extract of color, white skin and ascorbic acid were calculated 0. 1505, 0. 1738 and 0. 1095 mg/mL respectively. The total phenolic content of color and white skin was 109. 5 and 105. 6 (mgGAE/g) and the total flavonoid content was 3. 53 and 3. 02 (mgQ/g), respectively. The presence of alkaloid in methanol extract of color skin and the presence of saponin and tannin in methanol extract of white skin was confirmed. Due to antibacterial properties of this medicinal plant can be used in produce antibiotics controlling of human pathogenic microorganisms.

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APA: Copy

Shojaemehr, Mohadeseh, & Alamholo, Mostafa. (2019). Antibacterial Activity of Alcoholic and Aqueous Extracts of Various Organs of Citrus medica on 10 Human Pathogenic in Vitro. IRANIAN JOURNAL OF MEDICAL MICROBIOLOGY, 13(4 ), 310-320. SID. https://sid.ir/paper/373549/en

Vancouver: Copy

Shojaemehr Mohadeseh, Alamholo Mostafa. Antibacterial Activity of Alcoholic and Aqueous Extracts of Various Organs of Citrus medica on 10 Human Pathogenic in Vitro. IRANIAN JOURNAL OF MEDICAL MICROBIOLOGY[Internet]. 2019;13(4 ):310-320. Available from: https://sid.ir/paper/373549/en

IEEE: Copy

Mohadeseh Shojaemehr, and Mostafa Alamholo, “Antibacterial Activity of Alcoholic and Aqueous Extracts of Various Organs of Citrus medica on 10 Human Pathogenic in Vitro,” IRANIAN JOURNAL OF MEDICAL MICROBIOLOGY, vol. 13, no. 4 , pp. 310–320, 2019, [Online]. Available: https://sid.ir/paper/373549/en

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