EFFECT OF A FOUR-WEEK ENDURANCE TRAINING PROGRAM ON SERUM CONCENTRATIONS AND PANCREAS TISSUE OF DIABETIC RATS

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SADEGHIPOUR HAMID REZA; AKBARZADEH SAMAD; SALESI MOHSEN; FARZADINIA PARVIZ

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Journal: Research in Medicine Year:2018 | Volume:42 | Issue:2 Page(s): 86-92

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Title

EFFECT OF A FOUR-WEEK ENDURANCE TRAINING PROGRAM ON SERUM CONCENTRATIONS AND PANCREAS TISSUE OF DIABETIC RATS

Author(s)

SADEGHIPOUR HAMID REZA | AKBARZADEH SAMAD | SALESI MOHSEN | FARZADINIA PARVIZ | Issue Writer Certificate

Keywords

BETATROPHINQ1

ENDURANCE TRAININGQ1

BETA CELLSQ2

Abstract

Backgroundm: BETATROPHIN is known as a new therapeutic target of pancreases tissue. The aim of the present study was to investigate the effect of ENDURANCE TRAINING program on BETATROPHIN serum concentrations and pathological changes of pancreas tissue in diabetic rats.Materials and Methods: In the present experimental study, male wistar rats (N=24) were divided into three groups of healthy control, diabetic control, and ENDURANCE TRAINING. After induction of diabetes, the training group performed four weeks of ENDURANCE TRAINING and BETATROPHIN concentrations were assessed using ELIZA. Also, the pancreatic tissue was evaluated using histological methods. Data were analyzed using one way ANOVA.Results: The results showed that BETATROPHIN serum concentration significantly decreased in diabetic control group (P£0.05), but no significant increase was observed in the training group (P³0.05). Compared with diabetic control groups, ENDURANCE TRAINING did not make any significant changes in insulin resistance and beta cell function (P³0.05). In ENDURANCE TRAINING group, the means of number and size of pancreatic islets and the number of b-cell were higher than those of diabetic control group.Conclusion: Although ENDURANCE TRAINING did not significantly increase the BETATROPHIN levels, it had a positive effect on the pancreatic tissue in diabetic rats.

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APA: Copy

SADEGHIPOUR, HAMID REZA, AKBARZADEH, SAMAD, SALESI, MOHSEN, & FARZADINIA, PARVIZ. (2018). EFFECT OF A FOUR-WEEK ENDURANCE TRAINING PROGRAM ON SERUM CONCENTRATIONS AND PANCREAS TISSUE OF DIABETIC RATS. PAJOUHESH DAR PEZESHKI, 42(2 ), 86-92. SID. https://sid.ir/paper/41969/en

Vancouver: Copy

SADEGHIPOUR HAMID REZA, AKBARZADEH SAMAD, SALESI MOHSEN, FARZADINIA PARVIZ. EFFECT OF A FOUR-WEEK ENDURANCE TRAINING PROGRAM ON SERUM CONCENTRATIONS AND PANCREAS TISSUE OF DIABETIC RATS. PAJOUHESH DAR PEZESHKI[Internet]. 2018;42(2 ):86-92. Available from: https://sid.ir/paper/41969/en

IEEE: Copy

HAMID REZA SADEGHIPOUR, SAMAD AKBARZADEH, MOHSEN SALESI, and PARVIZ FARZADINIA, “EFFECT OF A FOUR-WEEK ENDURANCE TRAINING PROGRAM ON SERUM CONCENTRATIONS AND PANCREAS TISSUE OF DIABETIC RATS,” PAJOUHESH DAR PEZESHKI, vol. 42, no. 2 , pp. 86–92, 2018, [Online]. Available: https://sid.ir/paper/41969/en

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