SUCCESSFUL TREATMENT OF SCLEROMYXEDEMA WITH IVIG: A CASE REPORT

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NIKSOLAT ROODPOSHTI FATEMEH; MAJIDI HADI; RAHMATPOUR ROKNI GHASEM; DASHTI DARGAHLOO SAEED; TABARESTANI MOHAMMAD; SADR SARA

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Journal: Journal of Mazandaran University of Medical Sciences Year:2018 | Volume:28 | Issue:160 Page(s): 173-181

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Title

SUCCESSFUL TREATMENT OF SCLEROMYXEDEMA WITH IVIG: A CASE REPORT

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Keywords

SCLEROMYXEDEMAQ1

TREATMENTQ3

CUTANEOUS INVOLVEMENTQ1

INTRAVENOUS IMMUNOGLOBULINQ3

Abstract

SCLEROMYXEDEMA (SM), a rare progressive cutaneous mucinosis with a systemic involvement, presents with progressive dermal mucin depositions, causing skin thickening. In addition to the skininvolvement and paraproteinemia, patients with SM also have other complications. The systems whichare commonly involved include the gastrointestinal, musculoskeletal, pulmonary, cardiovascular, renal, and central nervous systems. SCLEROMYXEDEMA is difficult to treat. We present a patient with severeSCLEROMYXEDEMA with cutaneous, gastrointestinal, musculoskeletal and renal manifestations. Followingfailed therapeutic attempts, she responded to TREATMENT with intravenous gammaglobulin (IVIG), prednisolone, and azathioprine. As a result of TREATMENT with IVIG, the patient showed dramaticimprovement in her clinical symptoms and remained in remission throughout the course of combinationIVIG infusions and prednisolone. We concluded that an IVIG-prednisolone combination may be aneffective novel TREATMENT of SCLEROMYXEDEMA.

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APA: Copy

NIKSOLAT ROODPOSHTI, FATEMEH, MAJIDI, HADI, RAHMATPOUR ROKNI, GHASEM, DASHTI DARGAHLOO, SAEED, TABARESTANI, MOHAMMAD, & SADR, SARA. (2018). SUCCESSFUL TREATMENT OF SCLEROMYXEDEMA WITH IVIG: A CASE REPORT. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 28(160 ), 173-181. SID. https://sid.ir/paper/45198/en

Vancouver: Copy

NIKSOLAT ROODPOSHTI FATEMEH, MAJIDI HADI, RAHMATPOUR ROKNI GHASEM, DASHTI DARGAHLOO SAEED, TABARESTANI MOHAMMAD, SADR SARA. SUCCESSFUL TREATMENT OF SCLEROMYXEDEMA WITH IVIG: A CASE REPORT. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2018;28(160 ):173-181. Available from: https://sid.ir/paper/45198/en

IEEE: Copy

FATEMEH NIKSOLAT ROODPOSHTI, HADI MAJIDI, GHASEM RAHMATPOUR ROKNI, SAEED DASHTI DARGAHLOO, MOHAMMAD TABARESTANI, and SARA SADR, “SUCCESSFUL TREATMENT OF SCLEROMYXEDEMA WITH IVIG: A CASE REPORT,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 28, no. 160 , pp. 173–181, 2018, [Online]. Available: https://sid.ir/paper/45198/en

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