THE DIAGNOSTIC VALUE OF BLOOD LEVEL OF CEA AND CA15-3 TUMOR MARKERS IN BREAST TUMOR WITH AXILLARY LYMPH NODE METASTASES

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

NAGHSHVAR F.; TORABIZADEH ZH.; EMADIAN O.; GAHREMANI M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Mazandaran University of Medical Sciences Year:2007 | Volume:16 | Issue:56 Page(s): 16-20

Download Full-Text

Persian Verion

View:

1,826

Download:

Cites:

Information Journal Paper

Title

THE DIAGNOSTIC VALUE OF BLOOD LEVEL OF CEA AND CA15-3 TUMOR MARKERS IN BREAST TUMOR WITH AXILLARY LYMPH NODE METASTASES

Author(s)

NAGHSHVAR F. | TORABIZADEH ZH. | EMADIAN O. | GAHREMANI M. | Issue Writer Certificate

Keywords

METASTATIC BREAST CANCER-CEA-CA15-3Q3

Abstract

Background and purpose: Breast cancer is the most common malignant tumor and the leading cause of carcinoma death in women, with more than 1.000.000 cases occuring world wide annually. Recently, particular attention has been paid to sensitive/rapid and cheap laboratory methods for diagnosis of metastatic breast cancer. Evaluation of serum tumor markers including CEA and CA15-3 is one of these methods.Materials and Methods: The study was performed on 150 patients with breast cancer in Imam Khomeini and Shafa hospitals-Sari, Iran(2004-2005).Before modified radical mastectomy procedure, blood level of CEA and CA15-3 was measured with an ELlSA method using CANAg kit, then mastectomy and axillary lymph node specimens were evaluated. The information was analyzed using SPSS 11 statistical software.Results: In our study, the patients were between 32-75 yrs (mean: 51.6 yrs). The patients were divided into two groups: I (89 cases): Breast cancer with axillary lymph node metastases.II (61cases): Breast cancer without axillary lymph node metastases.Statistical differences was observed between the amount of CEA and CA15-3 in the two groups (P<5%).CA15-3 and CEA showed the best efficiency in the level of 35 u/ml and 2.5u/ml, respectively. Sensitivity and specificity of CA15-3 are 78% and 88%, respectively. Sensitivity and specificity of CEA are 48% and 83%, respectively.Conclusion: CA15-3 tumor marker is useful for diagnosis of metastatic cases but CEA tumor marker does not have optimal sensitivity.

Cites

No record.

References

No record.

Cite

APA: Copy

NAGHSHVAR, F., TORABIZADEH, ZH., EMADIAN, O., & GAHREMANI, M.. (2007). THE DIAGNOSTIC VALUE OF BLOOD LEVEL OF CEA AND CA15-3 TUMOR MARKERS IN BREAST TUMOR WITH AXILLARY LYMPH NODE METASTASES. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 16(56), 16-20. SID. https://sid.ir/paper/45626/en

Vancouver: Copy

NAGHSHVAR F., TORABIZADEH ZH., EMADIAN O., GAHREMANI M.. THE DIAGNOSTIC VALUE OF BLOOD LEVEL OF CEA AND CA15-3 TUMOR MARKERS IN BREAST TUMOR WITH AXILLARY LYMPH NODE METASTASES. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2007;16(56):16-20. Available from: https://sid.ir/paper/45626/en

IEEE: Copy

F. NAGHSHVAR, ZH. TORABIZADEH, O. EMADIAN, and M. GAHREMANI, “THE DIAGNOSTIC VALUE OF BLOOD LEVEL OF CEA AND CA15-3 TUMOR MARKERS IN BREAST TUMOR WITH AXILLARY LYMPH NODE METASTASES,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 16, no. 56, pp. 16–20, 2007, [Online]. Available: https://sid.ir/paper/45626/en

Related Journal Papers