STUDY OF VIRAL CO -INFECTIONS IN HAEMOPHILIC PATIENTS POSSESSING HEPATITIS C

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JEDARI SEYFI S.

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Journal: MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES Year:2008 | Volume:30 | Issue:3 Page(s): 27-30

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Title

STUDY OF VIRAL CO -INFECTIONS IN HAEMOPHILIC PATIENTS POSSESSING HEPATITIS C

Author(s)

JEDARI SEYFI S. | Issue Writer Certificate

Keywords

HAEMOPHILIC PATIENTSQ3

HEPATITIS BQ3

HEPATITIS CQ3

CYTOMEGALOVIRUSQ3

EPSTEIN BARR VIRUSQ3

Abstract

Background and Objectives: The Clotting - factor concentration (CFC) used for prophylaxis or treatments of haemorrhage in patients with haemophylia are a potential source of transmission of blood- borne viruses. Therefore, the study of these viruses is important and necessary in these patients.Materials and Methods: In this study 52 HAEMOPHILIC PATIENTS, positive for HEPATITIS C virus antibodies (anti- HCV) and negative for HIV, were randomly selected as case group. The same number of haemophylic patient’s age and sex matched and anti- HCV and HIV antibodies negative, were selected and studied as a control group. All serum samples were studied for HBsAg, CMV and EBV specific antibodies using ELISA method. Alanine Amino Transferase (ALT) and Aspartate Amino Transferase (AST) were performed with the standard methods in these patients and controls.Results: Our findings indicated that 7.6%, 61.5% and 57.6% of patients and 3.8%, 42% and 48% of the control group were positive for HBsAg, CMV and EBV specific IgG antibodies respectively. Significant correlation was only noticed in the case of CMV between the both groups (p=049). Serum ALT and AST were higher in both groups but significantly higher in the case group. More than 50% co - infection was noticed in the both groups. The serum ALT and AST activity in these groups were higher than the other groups.Conclusion: In spite of using controlled blood products by HAEMOPHILIC PATIENTS, they are still one of the high risk groups for blood - borne viruses. Therefore the study of these patients for above mentioned viruses is probably necessary for individual and social health.

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کاربرد بالینی خون و فرآورده های خونی

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APA: Copy

JEDARI SEYFI, S.. (2008). STUDY OF VIRAL CO -INFECTIONS IN HAEMOPHILIC PATIENTS POSSESSING HEPATITIS C. MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, 30(3), 27-30. SID. https://sid.ir/paper/47295/en

Vancouver: Copy

JEDARI SEYFI S.. STUDY OF VIRAL CO -INFECTIONS IN HAEMOPHILIC PATIENTS POSSESSING HEPATITIS C. MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2008;30(3):27-30. Available from: https://sid.ir/paper/47295/en

IEEE: Copy

S. JEDARI SEYFI, “STUDY OF VIRAL CO -INFECTIONS IN HAEMOPHILIC PATIENTS POSSESSING HEPATITIS C,” MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, vol. 30, no. 3, pp. 27–30, 2008, [Online]. Available: https://sid.ir/paper/47295/en

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