ISOLATION IDENTIFICATION AND QUANTITATIVE DETERMINATION OF GINGEROLS IN GINGER ROOTS

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NAZEMIEH H.; DELAZAR A.; AFSHAR J.; ESKANDARI B.

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Journal: PHARMACEUTICAL SCIENCES Year:2002 | Volume:- | Issue:2 Page(s): 61-68

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Title

ISOLATION IDENTIFICATION AND QUANTITATIVE DETERMINATION OF GINGEROLS IN GINGER ROOTS

Author(s)

NAZEMIEH H. | DELAZAR A. | AFSHAR J. | ESKANDARI B. | Issue Writer Certificate

Keywords

[6]-GINGEROLQ3

GINGERQ3

ISOLATION OF GINGEROLSQ3

Abstract

The rhizomes of GINGER were obtained from local market and then macroscopic and microscopic properties of powder evaluated. The charactristic components were similar with Zingiber officinal. Ground rhizomes were repeatedly extracted with acetone on room temperature and then combined extractes were evaporated in vacuum to afford a residue, which diluted by distilled water and extracted with petroleum ether and ethyl acetate respectively. The evolutions with TLC showed that the most of active ingredients present in petroleum ether fraction. The remaining of this extract after evaporation of solvent was fractionated on silicagel column (silica gel G60 70-230 Mesh, Merck) using gradient of Petr. Ether/EtoAc (92.5:7.5-90:10) and Petr. Ether/EtoAc/CHC13 (80:15:15-55:40:5) to afford 7 main groups of fractions. Fractions 4-7 were purified by prep. TLC method and finally the [6] - GINGERol and mixture of [8] and [10] GINGERol were obtained. Using UV, IR, IH-NMR and 13C-NMR the presence of these components in GINGER rhizome, dacumented. Quantitative analysis of these compounds showed that the [6] GINGERol, mixture of [8], [10]- GINGERoles and total amount of GINGERols in the rhizome were 4.96%, 6.43% and 11.04% respectively.

Cites

THE EFFECT ACUTE CONSUMPTION OF GINGER EXTRACT ON DELAYED ONSET MUSCLE SORENESS AFTER ONE SESSION EXERCISE IN FEMALE

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APA: Copy

NAZEMIEH, H., DELAZAR, A., AFSHAR, J., & ESKANDARI, B.. (2002). ISOLATION IDENTIFICATION AND QUANTITATIVE DETERMINATION OF GINGEROLS IN GINGER ROOTS. PHARMACEUTICAL SCIENCES, -(2), 61-68. SID. https://sid.ir/paper/48721/en

Vancouver: Copy

NAZEMIEH H., DELAZAR A., AFSHAR J., ESKANDARI B.. ISOLATION IDENTIFICATION AND QUANTITATIVE DETERMINATION OF GINGEROLS IN GINGER ROOTS. PHARMACEUTICAL SCIENCES[Internet]. 2002;-(2):61-68. Available from: https://sid.ir/paper/48721/en

IEEE: Copy

H. NAZEMIEH, A. DELAZAR, J. AFSHAR, and B. ESKANDARI, “ISOLATION IDENTIFICATION AND QUANTITATIVE DETERMINATION OF GINGEROLS IN GINGER ROOTS,” PHARMACEUTICAL SCIENCES, vol. -, no. 2, pp. 61–68, 2002, [Online]. Available: https://sid.ir/paper/48721/en

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