VITAMIN D RECEPTOR GENE BSMI POLYMORPHISMS IN SYSTEMIC LUPUS ERYTHEMATOSUS AND HEALTHY SUBJECTS

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ABBASI M.; REZAEI YAZDI Z.; TAVAKOL AFSHARI J.; HATEF M.R.; SAHEBARI M.; YARJANLI M.

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Journal: Journal of Inflammatory Diseases (The Journal of Qazvin University of Medical Science) Year:2009 | Volume:13 | Issue:1 (50) Page(s): 29-33

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Title

VITAMIN D RECEPTOR GENE BSMI POLYMORPHISMS IN SYSTEMIC LUPUS ERYTHEMATOSUS AND HEALTHY SUBJECTS

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Keywords

SYSTEMIC LUPUS ERYTHEMATOSUSQ2

POLYMORPHISMSQ2

VITAMIN DQ2

BSMI GENEQ3

POLYMORPHISMQ3

Abstract

Background: VITAMIN D receptor (VDR) gene POLYMORPHISMS/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank"> POLYMORPHISMS cause functional differences in immunomodulatory action of VITAMIN D. An association between VDR gene BSMI POLYMORPHISMS/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank"> POLYMORPHISMS and SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) has been documented. Objective: To compare the VDR gene BSMI POLYMORPHISMS/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank"> POLYMORPHISMS in patients with SLE and healthy controls.Methods: This was a case-control study conducted in the city of Mashhad (Iran). Sixty patients with lupus from two outpatient rheumatology clinics and 45 non-relative healthy controls of the same sex were selected using the census procedure. VDR gene typing was performed based on polymerase chain reaction–restriction fragment length POLYMORPHISM (PCR-RFLP). The results were analyzed using chi square test while a p<0.05 was considered as significant.Findings: The distribution of VDR genotyping of BSMI POLYMORPHISMS/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank"> POLYMORPHISMS in patients with SLE were 23.3% for BB, 60% for Bb and 16.7% for bb. Similarly, the values found for healthy group were 33.3%, 46.7%, and 20% for BB, Bb, and bb, respectively. There was no statistically significant difference between two groups. Conclusion: No significant difference in relative frequency of VDR gene BSMI POLYMORPHISMS/fa?page=1&sort=1&ftyp=all&fgrp=all&fyrs=all" target="_blank"> POLYMORPHISMS in SLE patients and healthy individuals was established.

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APA: Copy

ABBASI, M., REZAEI YAZDI, Z., TAVAKOL AFSHARI, J., HATEF, M.R., SAHEBARI, M., & YARJANLI, M.. (2009). VITAMIN D RECEPTOR GENE BSMI POLYMORPHISMS IN SYSTEMIC LUPUS ERYTHEMATOSUS AND HEALTHY SUBJECTS. JOURNAL OF INFLAMMATORY DISEASES (THE JOURNAL OF QAZVIN UNIVERSITY OF MEDICAL SCIENCES), 13(1 (50)), 29-33. SID. https://sid.ir/paper/48771/en

Vancouver: Copy

ABBASI M., REZAEI YAZDI Z., TAVAKOL AFSHARI J., HATEF M.R., SAHEBARI M., YARJANLI M.. VITAMIN D RECEPTOR GENE BSMI POLYMORPHISMS IN SYSTEMIC LUPUS ERYTHEMATOSUS AND HEALTHY SUBJECTS. JOURNAL OF INFLAMMATORY DISEASES (THE JOURNAL OF QAZVIN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2009;13(1 (50)):29-33. Available from: https://sid.ir/paper/48771/en

IEEE: Copy

M. ABBASI, Z. REZAEI YAZDI, J. TAVAKOL AFSHARI, M.R. HATEF, M. SAHEBARI, and M. YARJANLI, “VITAMIN D RECEPTOR GENE BSMI POLYMORPHISMS IN SYSTEMIC LUPUS ERYTHEMATOSUS AND HEALTHY SUBJECTS,” JOURNAL OF INFLAMMATORY DISEASES (THE JOURNAL OF QAZVIN UNIVERSITY OF MEDICAL SCIENCES), vol. 13, no. 1 (50), pp. 29–33, 2009, [Online]. Available: https://sid.ir/paper/48771/en

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