A COMPARISON OF THE HEMODYNAMIC CHANGES AND RECOVERY TIME OF PROPOFOL AND REMIFENTANIL WITH PROPOFOL AND ALFENTAILIN CATARCAT SURGERY ANESTHESIA

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AMINI SH.; KHOSHFETRAT M.

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Paper Information

Journal: JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE Year:2005 | Volume:27 | Issue:49 Page(s): 21-27

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Title

A COMPARISON OF THE HEMODYNAMIC CHANGES AND RECOVERY TIME OF PROPOFOL AND REMIFENTANIL WITH PROPOFOL AND ALFENTAILIN CATARCAT SURGERY ANESTHESIA

Author(s)

AMINI SH. | KHOSHFETRAT M. | Issue Writer Certificate

Keywords

PROPOFOL + ALFENTANYLQ3

PROPOFOL + REMIFENTANILQ4

CATARACT SURGERYQ3

Abstract

Background and Objective: Laryngoscopy and tracheal intubation may be accompanied by tachycardia, hypertension, and mycocardial ischemia in susceptible individuals. Materials and Methods: In a single blinded study, we compared hemodynamic effects and recovery time of remifentanil and prpofol (group I) with alfentanil and prpofol (group 11)for anesthesia in CATARACT SURGERY. The study was clinical trial and single blinded. It was performed in 60 patients in ASA Class II assigned for elective CATARACT SURGERY under general anesthesia. They were allocated consequently into two groups. After receiving ringer solution 5 ml/kg, patients in group 1 received alfentanil 20, μg/kg and those in group 2 received remifentanil 1 , μg/kg each 30 seconds. Propofol was administered 1.5 mg/kg for induction of anesthesia and cisatracurium 0.15 mg/kg for ETintubation. Anesthesia was maintained in group I with propofol (50-100, μg/kg/min), and remifentanil (0.1 μg/kg/min) in group 2 to keep BIS in a range of 50-60), and alfentanil (1, μg/kg/min).SBP and HR of the patients were recorded at pre-determined times. Extubation time (ET) and recovery time (RT) were also recorded in both groups one hour after discharge from recovery room. The patients were asked for amnesia during anesthesia. Results: HR and SBP of patients reduced in the two groups after induction of anesthesia but this reduction was not significant (SBP: 114.89 mmHg in alfentanil group vs. 113.71 mmHg in remifentanil group; HR: 69.13 bpm in alfentanil vs. 65.42 in remifentanil group; (p>0.05). The hemodynamic changes were not significantly different between the two groups (p> 0.05). SBP and HR during laryngoscopy and intubation did not increase significantly (SBP: 114.23 mmHg in alfentanil group vs. 110.53 mmHg in remifentanil group: HR: 66.03 bpm in alfentanil vs. 63.50 in remifentanil group; (p>0.05). The extubation time and discharge time from the Recovery room were 10.7 (±1.94) and 13.93 (±73.85) minutes, and 5 (±1.94) and 7.03 (±1.89) minutes in group I and 11respectively (p> 0.005). None of the patients declared any recall of events that happened during the anesthesia. Conclusion: We concluded that the compound of propofol and remifentanil can be used as a safe substitute for the compound of propofol and alfentanil for eye surgery, without significant hemodynamic changes. We also found that the recovery time was shorter in the propofol and remifentanil group. The only problem concerning the widespread use of remifentanil is its higher price compared to alfentanil.

Cites

COMPARING THE EFFECTS OF REMIFENTANIL AND ALFENTANIL ON THE CARDIOVASCULAR RESPONSES TO THE INDUCTION OF ANESTHESIA AND TRACHEAL INTUBATION IN ELDERLY PATIENTS

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APA: Copy

AMINI, SH., & KHOSHFETRAT, M.. (2005). A COMPARISON OF THE HEMODYNAMIC CHANGES AND RECOVERY TIME OF PROPOFOL AND REMIFENTANIL WITH PROPOFOL AND ALFENTAILIN CATARCAT SURGERY ANESTHESIA. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, 27(49), 21-27. SID. https://sid.ir/paper/63426/en

Vancouver: Copy

AMINI SH., KHOSHFETRAT M.. A COMPARISON OF THE HEMODYNAMIC CHANGES AND RECOVERY TIME OF PROPOFOL AND REMIFENTANIL WITH PROPOFOL AND ALFENTAILIN CATARCAT SURGERY ANESTHESIA. JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE[Internet]. 2005;27(49):21-27. Available from: https://sid.ir/paper/63426/en

IEEE: Copy

SH. AMINI, and M. KHOSHFETRAT, “A COMPARISON OF THE HEMODYNAMIC CHANGES AND RECOVERY TIME OF PROPOFOL AND REMIFENTANIL WITH PROPOFOL AND ALFENTAILIN CATARCAT SURGERY ANESTHESIA,” JOURNAL OF IRANIAN SOCIETY ANAESTHESIOLOGY AND INTENSIVE CARE, vol. 27, no. 49, pp. 21–27, 2005, [Online]. Available: https://sid.ir/paper/63426/en

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