SPECIFICITY OF RECOMBINANT P39 PROTEIN IN DETECTION OF ANTI-BRUCELLA ANTIBODY IN PATIENTS WITH BRUCELLOSIS

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ABTAHI H.; SALMANIAN A.H.; RAFATI S.

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Journal Paper

Paper Information

Journal: Journal of Arak University Medical Sciences Year:2006 | Volume:9 | Issue:1 (34) Page(s): 1-6

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Title

SPECIFICITY OF RECOMBINANT P39 PROTEIN IN DETECTION OF ANTI-BRUCELLA ANTIBODY IN PATIENTS WITH BRUCELLOSIS

Author(s)

ABTAHI H. | SALMANIAN A.H. | RAFATI S. | Issue Writer Certificate

Keywords

BRUCELLA ABORTUSQ3

RECOMBINANT P39 PROTEINQ3

ANTIGENICITYQ3

WESTERN BLOTQ3

Abstract

Introduction: In many studies, immunogenicity of Brucella proteins such as P39 in animals is investigated. In this study, we evaluated ANTIGENICITY of recombinant P39 from BRUCELLA ABORTUS in patients with Brucellosis. Materials and Methods: In this experimental study, at first recombinant P39 was produced in Escherichia coli. Sera reactivity of six infected individuals against the RECOMBINANT P39 PROTEIN was analysed by WESTERN BLOT.Results: Data indicated that P39 protein from BRUCELLA ABORTUS was recognized by patients, sera antibodies.Conclusion: Our data showed that RECOMBINANT P39 PROTEIN can be detected as an antigen by sera in infected human. Therefore, recombinant P39 have same epitopes with natural form of this antigen.

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References

EXPRESSION OF RECOMBINANT P39 PROTEIN FROM BRUCELLA ABORTUS IN ESCHERICHIA COLI

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APA: Copy

ABTAHI, H., SALMANIAN, A.H., & RAFATI, S.. (2006). SPECIFICITY OF RECOMBINANT P39 PROTEIN IN DETECTION OF ANTI-BRUCELLA ANTIBODY IN PATIENTS WITH BRUCELLOSIS. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), 9(1 (34)), 1-6. SID. https://sid.ir/paper/69206/en

Vancouver: Copy

ABTAHI H., SALMANIAN A.H., RAFATI S.. SPECIFICITY OF RECOMBINANT P39 PROTEIN IN DETECTION OF ANTI-BRUCELLA ANTIBODY IN PATIENTS WITH BRUCELLOSIS. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ)[Internet]. 2006;9(1 (34)):1-6. Available from: https://sid.ir/paper/69206/en

IEEE: Copy

H. ABTAHI, A.H. SALMANIAN, and S. RAFATI, “SPECIFICITY OF RECOMBINANT P39 PROTEIN IN DETECTION OF ANTI-BRUCELLA ANTIBODY IN PATIENTS WITH BRUCELLOSIS,” ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), vol. 9, no. 1 (34), pp. 1–6, 2006, [Online]. Available: https://sid.ir/paper/69206/en

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