COMPARISON OF ANTIOXIDANT SYSTEM IN PATIENTS WITH ISCHEMIC HEART DISEASE AND CONTROL GROUP AND ITS RELATION TO CERULOPLASMIN

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

GHOLAM HOSSEINIAN A.; MOHAMMADI GH.A.; YEGANEH M.; ZAHMATKESH H.; NAZARI M.; NAKHAEI N.

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES Year:2006 | Volume:4 | Issue:4-B (17) Page(s): 300-305

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

933

Download:

Cites:

Information Journal Paper

Title

COMPARISON OF ANTIOXIDANT SYSTEM IN PATIENTS WITH ISCHEMIC HEART DISEASE AND CONTROL GROUP AND ITS RELATION TO CERULOPLASMIN

Author(s)

Keywords

ANTIOXIDANT SYSTEMQ4

LIPID PEROXIDATIONQ2

ISCHEMIC HEART DISEASEQ4

CERULOPLASMINQ4

Abstract

Background and Objective: Coronary heart diseases, specially myocardial ischemias due to atherosclerosis, are among the major causes of mortality in industrialized societies. Oxidative stress occurs during ischemia. This finding has been confirmed by in vitro studies which have shown some changes in antioxidant concentration during ischemia. However, ANTIOXIDANT SYSTEM status and its relation to CERULOPLASMIN as a risk factor have not been studied in patients with ISCHEMIC HEART DISEASE (IHD). This study was conducted to evaluate this status. Materials and Methods: This case-control study carried out on 99 men, aged 35-55 years. Two groups including 29 patients with IHD due to coronary artery stenosis above 70 percent, confirmed by angiography and exercise tests, and 70 healthy men without heart disease, diabetes and hypertension background were studied. Blood samples were collected from all subjects early in the morning. Then catalase and superoxide dismutase (SOD) activities, total antioxidant of serum (TAS), CERULOPLASMIN and malondialdehyde (MDA) concentrations were measured by a spectrophotometric method.Results: TAS, SOD and catalase levels were 0.9±0.04 mmol/L, 1224±21.40 U/g Hb and 5657±290.60 U/g Hb respectively in patients which were significantly lower than those of controls 1.6±0.02 mmol/L, 1488±13.03 U/g Hb and 7546±176.80 U/g Hb (p<0.05). MDA and CERULOPLASMIN concentrations were 36±0.92 mg/dl, 277±6.90 nmol/g Hb) respectively in cases and 29±0.60 mg/dl and 247±4.20 nmol/g Hb in controls which showed a significant difference (p<0.05). There was no statistical correlation between antioxidants and CERULOPLASMIN level in these groups. Conclusion: In patients with IHD, ANTIOXIDANT SYSTEM capacity was lower than that of controls which can explain higher LIPID PEROXIDATION in these patients. Also we can not predict LIPID PEROXIDATION severity by measuring CERULOPLASMIN level because no association was found between these two factors.

Cites

No record.

References

No record.

Cite

APA: Copy

GHOLAM HOSSEINIAN, A., MOHAMMADI, GH.A., YEGANEH, M., ZAHMATKESH, H., NAZARI, M., & NAKHAEI, N.. (2006). COMPARISON OF ANTIOXIDANT SYSTEM IN PATIENTS WITH ISCHEMIC HEART DISEASE AND CONTROL GROUP AND ITS RELATION TO CERULOPLASMIN. JOURNAL OF RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES, 4(4-B (17)), 300-305. SID. https://sid.ir/paper/71395/en

Vancouver: Copy

GHOLAM HOSSEINIAN A., MOHAMMADI GH.A., YEGANEH M., ZAHMATKESH H., NAZARI M., NAKHAEI N.. COMPARISON OF ANTIOXIDANT SYSTEM IN PATIENTS WITH ISCHEMIC HEART DISEASE AND CONTROL GROUP AND ITS RELATION TO CERULOPLASMIN. JOURNAL OF RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES[Internet]. 2006;4(4-B (17)):300-305. Available from: https://sid.ir/paper/71395/en

IEEE: Copy

A. GHOLAM HOSSEINIAN, GH.A. MOHAMMADI, M. YEGANEH, H. ZAHMATKESH, M. NAZARI, and N. NAKHAEI, “COMPARISON OF ANTIOXIDANT SYSTEM IN PATIENTS WITH ISCHEMIC HEART DISEASE AND CONTROL GROUP AND ITS RELATION TO CERULOPLASMIN,” JOURNAL OF RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES, vol. 4, no. 4-B (17), pp. 300–305, 2006, [Online]. Available: https://sid.ir/paper/71395/en

Related Journal Papers