Up-Regulation of miR-21, miR-25, miR-93, and miR-106b in Gastric Cancer

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

LARKI PEGAH; AHADI ALIREZA; ZARE ALI; TARIGHI SHAHRIAR; Zaheri Mahrokh; Souri Mojgan; ZALI MOHAMMAD REZA; GHAEDI HAMID; OMRANI MIR DAVOOD

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Biomedical Journal Year:2018 | Volume:22 | Issue:6 Page(s): 367-373

Download Full-Text

View:

147

Download:

122

Cites:

Information Journal Paper

Title

Up-Regulation of miR-21, miR-25, miR-93, and miR-106b in Gastric Cancer

Author(s)

Keywords

Biomarkers

microRNAs

Stomach cancer

Abstract

Background: Differential expression profile of microRNAs (miRNAs) could be a diagnosis signature for monitoring gastric cancer (GC) progression. In this study, we focus on the comparison of expression levels of miR-21, miR-25, miR-93, miR-106b, and miR-375 during the sequential pattern of GC development, including normal gastric, gastric dysplasia, and GC sample. Methods: We used SYBR Green-based quantitative-PCR to quantify miRNAs expression. Results: Our analysis revealed the increased expression levels of miR-21 (p = 0. 034), miR-25 (p = 0. 0003), miR-93 (p = 0. 0406), and miR-106b (p = 0. 023) in GC samples. In addition, GC patients with positive lymph node metastasis showed the up-regulation of miR-25, miR-93, and miR-106b (p < 0. 05). Conclusion: Our findings suggested that the expression of miR-21, miR-25, miR-93, and miR-106b altered in GC, and some of them may be further investigated as Biomarkers for GC early detection and prognosis prediction.

Cites

Correlation between the Expression Levels of Circulating miR-21 and miR-192 and Clinicopathological Features in Plasma of Patients with Gastric Cancer in Iran

References

No record.

Cite

APA: Copy

LARKI, PEGAH, AHADI, ALIREZA, ZARE, ALI, TARIGHI, SHAHRIAR, Zaheri, Mahrokh, Souri, Mojgan, ZALI, MOHAMMAD REZA, GHAEDI, HAMID, & OMRANI, MIR DAVOOD. (2018). Up-Regulation of miR-21, miR-25, miR-93, and miR-106b in Gastric Cancer. IRANIAN BIOMEDICAL JOURNAL, 22(6), 367-373. SID. https://sid.ir/paper/759166/en

Vancouver: Copy

LARKI PEGAH, AHADI ALIREZA, ZARE ALI, TARIGHI SHAHRIAR, Zaheri Mahrokh, Souri Mojgan, ZALI MOHAMMAD REZA, GHAEDI HAMID, OMRANI MIR DAVOOD. Up-Regulation of miR-21, miR-25, miR-93, and miR-106b in Gastric Cancer. IRANIAN BIOMEDICAL JOURNAL[Internet]. 2018;22(6):367-373. Available from: https://sid.ir/paper/759166/en

IEEE: Copy

PEGAH LARKI, ALIREZA AHADI, ALI ZARE, SHAHRIAR TARIGHI, Mahrokh Zaheri, Mojgan Souri, MOHAMMAD REZA ZALI, HAMID GHAEDI, and MIR DAVOOD OMRANI, “Up-Regulation of miR-21, miR-25, miR-93, and miR-106b in Gastric Cancer,” IRANIAN BIOMEDICAL JOURNAL, vol. 22, no. 6, pp. 367–373, 2018, [Online]. Available: https://sid.ir/paper/759166/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops