TREATMENT OF VAGINAL CANDIDIASIS BY ETHANOLIC EXTRACT OF PROPOLIS IN RABBIT

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OWNAGH A.; ADIB HESAMI M.

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Journal: Armaghane Danesh Year:2012 | Volume:17 | Issue:3 (69) Page(s): 233-242

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Information Journal Paper

Title

TREATMENT OF VAGINAL CANDIDIASIS BY ETHANOLIC EXTRACT OF PROPOLIS IN RABBIT

Author(s)

OWNAGH A. | ADIB HESAMI M. | Issue Writer Certificate

Keywords

RABBITQ3

VAGINITISQ3

CANDIDA ALBICANSQ2

PROPOLISQ2

NYSTATINQ2

Abstract

Background & aim: PROPOLIS is a resinous substance collected by honeybees from buds and leaves of trees and plants, possessing various biological properties. This study aimed to assess the anti-fungal activities of Ethanolic extract of PROPOLIS (EEP) in an experimental infection of vaginal candidiasis.Methods: In this study, twenty-four female RABBITs were used for experimental infections. Animals were randomly divided into six equal groups: positive control group, negative control group, and four treatment groups. The four test groups were given doses of 125, 250, 500 and 1000 mg/ml of PROPOLIS Ethanolic extract respectively while the positive control group received the standard NYSTATIN treatment and negative control group were given saline, locally, two times a day for 20 days. The data were analyzed, using descriptive statistics.Results: Among all groups, the results showed that dose of 1000 mg/ml of EEP were the most effective dose in treatment of experimental vaginal candidiasis. Clinical signs of vaginal candidiasis were healed in NYSTATIN group after 9 days. No effect was recorded after 20 days treatment of infection for others doses of EEP that were used in this study.Conclusion: It can be concluded that Ethanolic extract of PROPOLIS in 1000 mg/ml concentration could treat experimental vaginal candidiasis in RABBITs in a shorter time in comparison with standard NYSTATIN treatment.

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APA: Copy

OWNAGH, A., & ADIB HESAMI, M.. (2012). TREATMENT OF VAGINAL CANDIDIASIS BY ETHANOLIC EXTRACT OF PROPOLIS IN RABBIT. ARMAGHAN DANESH, 17(3 (69)), 233-242. SID. https://sid.ir/paper/77796/en

Vancouver: Copy

OWNAGH A., ADIB HESAMI M.. TREATMENT OF VAGINAL CANDIDIASIS BY ETHANOLIC EXTRACT OF PROPOLIS IN RABBIT. ARMAGHAN DANESH[Internet]. 2012;17(3 (69)):233-242. Available from: https://sid.ir/paper/77796/en

IEEE: Copy

A. OWNAGH, and M. ADIB HESAMI, “TREATMENT OF VAGINAL CANDIDIASIS BY ETHANOLIC EXTRACT OF PROPOLIS IN RABBIT,” ARMAGHAN DANESH, vol. 17, no. 3 (69), pp. 233–242, 2012, [Online]. Available: https://sid.ir/paper/77796/en

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