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Information Journal Paper

Title

Cyclodextrins: Concept to applications, regulatory issues and challenges

Pages

  202-214

Abstract

 Background: Solubility properties of drugs intensify a crucial role during the formulation development process. Water solubility is one of the utmost important factor concerning drug bioavailability analysis. Cyclodextrins are supportive, competent excipients, required an ever-rising way to disguise unwanted pharmaceutical characteristics, exclusively poor aqueous solubility. Main Text: CDs are actively useful in medicinal industries for copious purposes, including improving drug solubility, safety, physicochemical stability, and bioavailability. Different solubility enhancement methods can resolve several approaches to trouble insolubility. Conclusions: Among all, the reported CDs complexation technique has been incorporated as one of the essential and imperative concepts to enhances the solubility, permeability, dissolution rate, and bioavailability of drugs. This review discusses some of the outcomes and broad solicitations of CDs and their derivatives in various drug delivery systems. This review also addresses the aspects regarding the new CD-based therapeutics, possible future uses and issues, and regulatory perspective in the modern scenario.

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    APA: Copy

    Mohammad, Azeez, & Singh, Sumer. (2020). Cyclodextrins: Concept to applications, regulatory issues and challenges. NANOMEDICINE RESEARCH JOURNAL, 5(3), 202-214. SID. https://sid.ir/paper/785194/en

    Vancouver: Copy

    Mohammad Azeez, Singh Sumer. Cyclodextrins: Concept to applications, regulatory issues and challenges. NANOMEDICINE RESEARCH JOURNAL[Internet]. 2020;5(3):202-214. Available from: https://sid.ir/paper/785194/en

    IEEE: Copy

    Azeez Mohammad, and Sumer Singh, “Cyclodextrins: Concept to applications, regulatory issues and challenges,” NANOMEDICINE RESEARCH JOURNAL, vol. 5, no. 3, pp. 202–214, 2020, [Online]. Available: https://sid.ir/paper/785194/en

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