THE LONG-TERM EFFECT OF HINOSAN ON SPERMATOGENESIS ON THE BALB/C MICE

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FATAHI ESMAEIL; JOURSARAEI S.GH.A.; PARIVAR KAZEM; MOGHADAMNIA ALI AKBAR

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Journal: JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES Year:2008 | Volume:9 | Issue:4 (24) Page(s): 5-10

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Title

THE LONG-TERM EFFECT OF HINOSAN ON SPERMATOGENESIS ON THE BALB/C MICE

Author(s)

FATAHI ESMAEIL | JOURSARAEI S.GH.A. | PARIVAR KAZEM | MOGHADAMNIA ALI AKBAR | Issue Writer Certificate

Keywords

ORGANOPHOSPHORUSQ3

HINOSANQ3

TESTIS REDUCETUEQ2

LEYDIG CELLSQ3

Abstract

Background & Objective: HINOSAN is organophosphates that inhibit acetylcolinesterase activity, which could be resulted in damages of genital organs. This compound has been used extensively in the agriculture, for pest control. Therefore, in the present study we investigated the effect of HINOSAN on spermatogenesis in mice. Materials & Methods: For this experimental study, the male mice were divided into three groups. In the cases group, mice were injected with HINOSAN consecutive doses (20mg/kg i.p, five consecutive days per week for one month), sham (normal saline) and control (no injection). Animals were scarified 7 days after the latest HINOSAN injection. Therefore, the mice testis sections were prepared and morphologic aspects of testis and spermatogenesis processes were examined. Data were analyzed using of one-way ANOVA. Significance was set at P<0.05. Results: The HINOSAN showed a significant decrease in number of germ cells, spermatocyt, spermatids, LEYDIG CELLS, blood vessels and also diameter of somniferous on testes of the mice decreased, compared with control groups (P<0.05). Conclusion: This study demenstrated that HINOSAN is effective on spermatogenesis and seminiferous tubule structure, also can decrease germinal cells

Cites

DIAZINON ALTERS SEX HORMONES, INTERFERON-GAMMA, INTERLEUKIN-4 AND 10 IN MALE WISTAR RATS

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APA: Copy

FATAHI, ESMAEIL, JOURSARAEI, S.GH.A., PARIVAR, KAZEM, & MOGHADAMNIA, ALI AKBAR. (2008). THE LONG-TERM EFFECT OF HINOSAN ON SPERMATOGENESIS ON THE BALB/C MICE. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, 9(4 (24)), 5-10. SID. https://sid.ir/paper/78881/en

Vancouver: Copy

FATAHI ESMAEIL, JOURSARAEI S.GH.A., PARIVAR KAZEM, MOGHADAMNIA ALI AKBAR. THE LONG-TERM EFFECT OF HINOSAN ON SPERMATOGENESIS ON THE BALB/C MICE. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2008;9(4 (24)):5-10. Available from: https://sid.ir/paper/78881/en

IEEE: Copy

ESMAEIL FATAHI, S.GH.A. JOURSARAEI, KAZEM PARIVAR, and ALI AKBAR MOGHADAMNIA, “THE LONG-TERM EFFECT OF HINOSAN ON SPERMATOGENESIS ON THE BALB/C MICE,” JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, vol. 9, no. 4 (24), pp. 5–10, 2008, [Online]. Available: https://sid.ir/paper/78881/en

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