DIAZINON ALTERS SEX HORMONES, INTERFERON-GAMMA, INTERLEUKIN-4 AND 10 IN MALE WISTAR RATS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MALIJI GH.; JOURSARAEI S.GH.A.; ZABIHI E.; FATTAHI E.; REZAIE E.; SOHAN FARAJI A.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES Year:2014 | Volume:16 | Issue:1 (49) Page(s): 22-28

Download Full-Text

Persian Verion

View:

864

Download:

Cites:

Information Journal Paper

Title

DIAZINON ALTERS SEX HORMONES, INTERFERON-GAMMA, INTERLEUKIN-4 AND 10 IN MALE WISTAR RATS

Author(s)

Keywords

DIAZINONQ2

INTERLEUKIN-10Q2

FSHQ2

LHQ2

TESTOSTERONEQ2

RATQ2

Abstract

Background and Objective: Agricultural toxins including organochlorine and organophosphorus families cause damages in the various tissues in humans. DIAZINON is a non-systemic organophosphate insecticide. This study was carried out to determine the effect of DIAZINON on sex hormone, interferon gamma, interleukin-4 and 10 in male RATs.Methods: In this experimental study 24 adult male Wistar RATs were randomly allocated into four groups. Three experimental groups were received DIAZINON 5 days per week for one month at 0.3, 3 and 30 mg/kg/bw intraperitoneally, while controls received nothing. Seven days after the last injection, blood samples were obtained and the serum TESTOSTERONE, FSH, LH, interferon gamma, interleukin-4 and INTERLEUKIN-10 were measured.Results: Serum level of INTERLEUKIN-10 significantly increased in experimental group (30 mg/kg/bw of DIAZINON) compared to controls (P<0.05). Serum level of INTERLEUKIN-10 significantly decreased in 0.3 mg/kg/bw and 3mg/kg/bw of DIAZINON groups compared to controls (P<0.05). Interleukin-4 level was only significant in the group receiving 30 mg/kg/bw of DIAZINON (P<0.05). Reduction in interferon-gamma level was not significant between control and experimental groups. FSH significantly reduced in the three experimental groups in comparison with controls (P<0.05). TESTOSTERONE level was significantly increased in experimental groups compared to control (P<0.05).Conclusion: DIAZINON increases INTERLEUKIN-10 and TESTOSTERONE and reduces FSH hormone in the RAT.

Cites

EFFECT OF DIAZINON ON PITUITARY-GONADAL AXIS AND HISTOLOGICAL ALTERATION OF SEMINFEROUS TUBULES IN ADULT RAT TESTIS

References

Cite

APA: Copy

MALIJI, GH., JOURSARAEI, S.GH.A., ZABIHI, E., FATTAHI, E., REZAIE, E., & SOHAN FARAJI, A.. (2014). DIAZINON ALTERS SEX HORMONES, INTERFERON-GAMMA, INTERLEUKIN-4 AND 10 IN MALE WISTAR RATS. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, 16(1 (49)), 22-28. SID. https://sid.ir/paper/79118/en

Vancouver: Copy

MALIJI GH., JOURSARAEI S.GH.A., ZABIHI E., FATTAHI E., REZAIE E., SOHAN FARAJI A.. DIAZINON ALTERS SEX HORMONES, INTERFERON-GAMMA, INTERLEUKIN-4 AND 10 IN MALE WISTAR RATS. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2014;16(1 (49)):22-28. Available from: https://sid.ir/paper/79118/en

IEEE: Copy

GH. MALIJI, S.GH.A. JOURSARAEI, E. ZABIHI, E. FATTAHI, E. REZAIE, and A. SOHAN FARAJI, “DIAZINON ALTERS SEX HORMONES, INTERFERON-GAMMA, INTERLEUKIN-4 AND 10 IN MALE WISTAR RATS,” JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, vol. 16, no. 1 (49), pp. 22–28, 2014, [Online]. Available: https://sid.ir/paper/79118/en

Related Journal Papers