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Information Journal Paper

Title

DETERMINATION THE EFFECTS OF EPIDERMAL GROWTH FACTOR ON DEVELOPMENTAL RATES OF PRE-IMPLANTATION MOUSE EMBRYO

Pages

  31-37

Abstract

 Purpose: To determine the effects of different doses of addition of exogenous EPIDERMAL GROWTH FACTOR (EGF) on development of pre-implantation MOUSE embryo.Materials and Methods: MOUSE zygotes, two cell, 8 cell any morulae were collected from superovulated NMRI mice 24, 48, 64 and 80 hrs after hCG injection, respectively. The obtained embryos were cultured on medium alone, medium with 1, 4 and 10 ng/ml of EGF and recorded daily for 96 hrs. The blastulation and hatching rates of every group were compared statistically using Chi-square Test.Results: The results showed that exogenous EGF could not help zygotes to overcome on developmental block. Also, the cleavage rate to two cell stage of treated zygotes were lower than non-treated zygotes. The hatching rates of two cell embryos treated with different doses of EGF and non-treated were almost identical. The hatching rates of eight cell and morula embryos treated with 10 ng/ml of EGF were significantly higher than other doses and control embryos.Conclusion: Exogenous EGF can improve PRE-IMPLANTATION EMBRYO development after eight cell stage but it can not affect the development of the stages before eight cell.

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    APA: Copy

    MOVAHEDIN, M., KOROUJI, S.M., & ANJAMROOZ, A.. (2003). DETERMINATION THE EFFECTS OF EPIDERMAL GROWTH FACTOR ON DEVELOPMENTAL RATES OF PRE-IMPLANTATION MOUSE EMBRYO. JOURNAL OF IRANIAN ANATOMICAL SCIENCES, 1(2), 31-37. SID. https://sid.ir/paper/81469/en

    Vancouver: Copy

    MOVAHEDIN M., KOROUJI S.M., ANJAMROOZ A.. DETERMINATION THE EFFECTS OF EPIDERMAL GROWTH FACTOR ON DEVELOPMENTAL RATES OF PRE-IMPLANTATION MOUSE EMBRYO. JOURNAL OF IRANIAN ANATOMICAL SCIENCES[Internet]. 2003;1(2):31-37. Available from: https://sid.ir/paper/81469/en

    IEEE: Copy

    M. MOVAHEDIN, S.M. KOROUJI, and A. ANJAMROOZ, “DETERMINATION THE EFFECTS OF EPIDERMAL GROWTH FACTOR ON DEVELOPMENTAL RATES OF PRE-IMPLANTATION MOUSE EMBRYO,” JOURNAL OF IRANIAN ANATOMICAL SCIENCES, vol. 1, no. 2, pp. 31–37, 2003, [Online]. Available: https://sid.ir/paper/81469/en

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    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
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