Background: Infant's growth and development is highly depended on maternal nutritional profile during the pregnancy and the infants feeding adequacy. With respect to the susceptibility of infants, evaluating their nutritional status is of great importance. Materials and methods: To determine the effects of iron, folate, vitamin Bl2 and A deficiencies on neonatal height and weight, 230 neouates borned in Shaheed Mofatteh hospital in Varamin, had entered this study. Serum folate, RBC folate, and serum Bl2 were determined using RIDA test, however, serum iron and TIBC were determined through Auto analyzer RA-1000. Meanwhile, transferrin saturation was calculated as below: (serum iron/TIBC) 100. Serum vitamin A was determined using Thomsom fluorimetric.Results: Results have implied that 8% and 8.9% of the infants were malnourished according to the birth weight and height, respectively. The mean of vitamin A concentration in serum and the proportions of polynuclears of newboms under-2500 gr were significantly lower than the normal-weighted newbons. The mean of proportions of lymphocytes and eozinophils of newbomes under-2500gr were significantly higher than normal-weighted newbomes. Deficiency of serum iron, TIBC, transferrin saturation, serum folate, RBC folate and serum Bl2 were reported in 0.5%, 2.5%, 2.5%, 22.7%, 3.8%, and 5.4% of the neouates, respectively. The prevalence of vitamin A deficiency was 27.1%, however, this was more prevalent among boys rather than girls (34.8% vs.17.1 %). A significant relationship was found between the weight and height of newborns and the serum vitamin A (p<0.03).Conclusion: Since vitamin A had important impact on fetal growth, height and weight changes and mortality could be due to its deficiency.