Journal of Isfahan Medical School
Year:2016 | Volume:34 | Issue:377|Papers Count:6

Background: Cinnamom (Cinnamonum verum) has therapeutic effects such as anti-diabetic, decreasing of weight and blood lipid and sugar. The aim of this study was to evaluate the effect of aqueous extract of Cinnamon on learning and spatial memory in streptozotocin-induced diabetic rats.Methods: In this study, 28 adult male Wistar rats weighting 200±30 g were used. Rats were divided into four groups: control (C), control receiving extract (C+C), diabetic (D), diabetic receiving extract (D+C). Diabetes was induced by intraperitoneal injection of 50 mg/kg streptozotocin. The experiments were assigned to 3 weeks. In this time, the treatment of extract was carried out in a dose of 200 mg/kg. At the end of experiment the weight of the treated rats was compared to control groups. Evaluation of learning and spatial memory was done using radial eight-arm maze. The data were analyzed using repeated measure ANOVA by SPSS software.Findings: The significant (P<0.05) increase of time for finding food in the diabetic, extract receiving and diabetic receiving extract rats compared to control group indicated the attenuating effects of cinnamon on rats’ learning and spatial memory.Conclusion: The aqueous extract of cinnamon attenuates the learning and the spatial memory of diabetic rats, probably due to increase of blood sugar and its destructive effects on nervous system function.

Background: Migraine is a common headache disorder, and patients with migraine commonly report vestibular symptoms. Although the relation between vestibular migraine and vestibular symptoms were investigated in many studies, the prevalence of vestibular symptoms in migraine patients without vestibular migraine type are less taken into consideration. Therefore, in this study we aimed to determine the prevalence of vestibular symptoms in patients with migraine in Isfahan, Iran.Methods: In a descriptive-analytic study, 400 patients with migraine were selected by convenience sampling. To determine the prevalence of vestibular symptoms in patients with migraine, a questionnaire consisting of 25 questions with 9 criteria was used.Findings: No significant differences were observed between patients with migraine with aura and patients with migraine without aura regarding to the symptoms including: sensation of spinning (P=0.03), ataxia (P=0.01) and a feeling of pressure in the head (P<0.01). The most prevalent vestibular symptoms were nausea (78%), lightheadedness (74.5%), and phonophobia (72.3%), respectively.Conclusion: Vestibular symptoms had a high prevalence among patients with migraine suggesting that maybe there is an association between these symptoms and pathophysiology of migraine. There was significant difference between the two groups of patients with migraine with aura and migraine without aura in terms of prevalence of vestibular symptoms that can be used diagnostically to differentiate between two these groups of patients.

Background: Stress is a migraine trigger. Anxiety sensitivity as a mediator between stress and disease is one of the factors affecting the symptoms of migraine. Purpose of the present study was to assess the effectiveness of Eye Movement Desensitization and Reprocessing (EMDR) on anxiety sensitivity in patients with migraine.Methods: In this semi experimental study, 36 patients with migraine were randomly divided into two groups: experimental and control. Patients of experimental group received EMDR therapy, 3 sessions of 90 minutes within three weeks. Control group did not receive any medical or psychological intervention. Participants in both groups were evaluated with Anxiety Sensitivity Inventory- Revised (ASI-R) during pre-test, post-test and one-month follow-up.Findings: The analysis of variance with repeated measures showed that eye movement desensitization and reprocessing reduces anxiety sensitivity (P<0.05) in patients.Conclusion: The results suggest that EMDR can be considered as one of the therapies for migraine headaches.

Background: Obstructive sleep apnea and stroke are the most common diseases worldwide and especially in our country. Previous studies showed that both above diseases are common risk factors and in some of study co-morbidity to stroke and obstructive sleep apnea were reported. Thus, considering the high prevalence of stroke and obstructive sleep apnea, the aim of this study was to determine the symptoms and risk factors of obstructive sleep apnea among patients with acute stroke who were hospitalized in Alzahra hospital, Isfahan, Iran during 2014.Methods: In a case control study, 55 stroke patients and 55 healthy persons were studied for obstructive sleep apnea. Sleepiness symptoms and risk factors of obstructive sleep apnea was measured by special checklist and comparison between the two groups was done by SPSS software.Findings: The mean of obstructive sleep apnea in case and control groups was 9.6±2.9 and 6.5±4.9 respectively and a significant difference between the two groups was seen (P<0.001). the mean of total number of risk factors of obstructive sleep apnea in the two groups was 9.5±2.9 and 6.4±4.8 respectively (P<0.001).29 (52.7%) of case group and 11 (20%) of control group had at least 10 numbers of obstructive sleep apnea symptoms and the difference between the two groups was significant (P<0.001).Conclusion: Notice to high prevalence and importance of obstructive sleep apnea and stroke and common risk factors of the two disease and noting the lack of studies about co-morbidity of obstructive sleep apnea and stroke, more study about the relation between stoke and obstructive sleep apnea was needed, also patients with obstructive sleep apnea mast identify and treatment and prevention programs must be done for these patients.

Background: Multiple sclerosis (MS) is a chronic disease of central nervous system, which affects economic, financial and emotional aspects in individuals, families and the society. The present study aimed to investigate the association between family caregivers’ quality of life and psychological capital of the patients with MS.Methods: This is a descriptive analytical cross-sectional study, conducted on 95 MS patients and their caregivers (total of 190 subjects) referring to MS Clinic of Alzahra hospital in Isfahan, Iran, who were selected through convenient sampling. Data collection tool was including demographic characteristics, quality of life and psychological capital. After data collection, the obtained data were analyzed by descriptive and analytical statistical tests through SPSS software.Findings: The results showed that caregivers’ mean score of quality of life was 52.7. Mean score of psychological wealth in domains of self-efficacy, hope, tolerance and optimism were 25.2, 19.5, 19.6 and 21.3, respectively. There was also a significant association between caregivers’ score of quality of life and MS patients’ score of psychological capital and its domains (P<0.05).Conclusion: The present study showed an association between MS patients’ family caregivers’ quality of life and MS patients’ psychological capital and its four domains among these patients. Consideration of MS patients’ family caregivers’ quality of life and its association with patients’ psychological capital is of great importance to facilitate their recovery, care and administration of efficient interventions to help their survival and recovery.