EFFECTS OF PURIFIED OMEGA –3 FATTY ACIDS IN POSTMENOPAUSAL WOMEN WITH TYPE 2 DIABETES

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SHIDFAR F.; YAR AHMADI SH.; JALALI M.; EFTEKHARI M.H.; HOSSEINI SHARIEH; AHARI L.

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Journal Paper

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Journal: Iranian Journal of Endocrinology & Metabolism Year:2007 | Volume:9 | Issue:3 (SN 35) Page(s): 229-234

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Title

EFFECTS OF PURIFIED OMEGA –3 FATTY ACIDS IN POSTMENOPAUSAL WOMEN WITH TYPE 2 DIABETES

Author(s)

Keywords

OMEGA –3 FATTY ACIDSQ3

POSTMENOPAUSAL WOMENQ2

TYPE2 DIABETESQ2

LIPOPROTEINQ3

GLUCOSEQ3

Abstract

Introduction: Omega 3 fatty acid (03FA) consumption has been shown to reduce risk factors for cardiovascular disease. TYPE 2 diabetes confers an adverse cardiovascular risk profile particularly in women after menopause. The aim of this study was to determine whether a dietary supplement with omega 3 fatty acids affected insulin resistance, glycemic control and cardiovascular risk markers in POSTMENOPAUSAL WOMEN with type 2 diabetes. A total of 32 postmenopausal overweight women with diet-controlled type 2 diabetes completed a randomized double blind parallel trial of purified omega 3 fatty acid supplementation (2g/day) versus placebo for 10 weeks. Evaluated were serum triglycerides (TG), HDL-c, total cholesterol (TC) and GLUCOSE using the enzymatic method, Insulin by radioimmunoassay and insulin resistance using the Homeostasis Model Assessment method (HOMA-IR) were calculated. Relative to those in the placebo group, TG decreased significantly (P=0.03) in the 03 FA group. 03 FA supplementation had no significant effect on serum LDL-c, HDL-c , GLUCOSE and insulin resistance but there was a significant increase in serum insulin and TC in the 03 FA group at the end of study compared to the beginning (P=0.04, P=0.04 respectively). Intake of 2g 03 FA had favorable effects on serum TG and TG/HDL-C, no effect of LDL-C, HDL-C, GLUCOSE and insulin resistance but did have an adverse effect on serum insulin and TC. Recommendation of 03FA intake in diabetic POSTMENOPAUSAL WOMEN needs further investigation.

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APA: Copy

SHIDFAR, F., YAR AHMADI, SH., JALALI, M., EFTEKHARI, M.H., HOSSEINI, SHARIEH, & AHARI, L.. (2007). EFFECTS OF PURIFIED OMEGA –3 FATTY ACIDS IN POSTMENOPAUSAL WOMEN WITH TYPE 2 DIABETES. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), 9(3 (SN 35)), 229-234. SID. https://sid.ir/paper/27435/en

Vancouver: Copy

SHIDFAR F., YAR AHMADI SH., JALALI M., EFTEKHARI M.H., HOSSEINI SHARIEH, AHARI L.. EFFECTS OF PURIFIED OMEGA –3 FATTY ACIDS IN POSTMENOPAUSAL WOMEN WITH TYPE 2 DIABETES. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM)[Internet]. 2007;9(3 (SN 35)):229-234. Available from: https://sid.ir/paper/27435/en

IEEE: Copy

F. SHIDFAR, SH. YAR AHMADI, M. JALALI, M.H. EFTEKHARI, SHARIEH HOSSEINI, and L. AHARI, “EFFECTS OF PURIFIED OMEGA –3 FATTY ACIDS IN POSTMENOPAUSAL WOMEN WITH TYPE 2 DIABETES,” IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), vol. 9, no. 3 (SN 35), pp. 229–234, 2007, [Online]. Available: https://sid.ir/paper/27435/en

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