THE EFFECT OF AQUEOUS EXTRACT THYMUS KOTSCHYANUS BOISS. ET HOHEN ON GLYCEMIC CONTROL AND DYSLIPIDEMIA ASSOCIATED WITH TYPE II DIABETES: A RANDOMIZED CONTROLLED TRIAL

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TALEB A.M.; QANNADI F.; CHANGIZI ASHTIYANI S.; ZAREI A.; REZVANFAR M.R.; AKBARI A.; HEKMATPOU D.

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Journal: IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM) Year:2017 | Volume:19 | Issue:4 Page(s): 234-243

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Title

THE EFFECT OF AQUEOUS EXTRACT THYMUS KOTSCHYANUS BOISS. ET HOHEN ON GLYCEMIC CONTROL AND DYSLIPIDEMIA ASSOCIATED WITH TYPE II DIABETES: A RANDOMIZED CONTROLLED TRIAL

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Keywords

DIABETES TYPE 2Q2

THYMUS KOTSCHYANUSQ1

DYSLIPIDEMIAQ2

Abstract

Introduction: The prevalence of diabetes mellitus, a major cause of death and disability, is increasing worldwide. Considering the data available on folk medicine in Iran, this study aimed to investigate hypoglycemic and hypolipidemic effects of the aqueous extract of the plant, THYMUS KOTSCHYANUS Boiss. et Hohen (Thymus. K)in patients with type II diabetes. Materials and Methods: This study is a clinical trial in which 64 patients, aged 30-60 years, with confirmed diagnosis of Type II diabetes treated with usual anti-diabetic drugs normally were randomly divided into two groups, 1. (receiving usual drugs) and 2. (Receiving Thymus. K aqueous extracts 20 gr/day with conventional therapy). Three months later, indicators of glycemic control and lipid profiles were reassessed in both groups and compared with baseline values respectively.Results: Results showed that the groups receiving the aqueous extractThymus. K (20 gr/day for three months) in addition to usual drugs, showed a significant decrease (p<0.05) in FBG and Hb A1C levels and a significant increase (p<0.05) in the beta cell function index (HOMA-Beta) while significantly reducing (p<0.05) is LDL-C levels.Conclusion: The aqueous extract of the plantThymus. K in patients with type II diabetes along with the usual anti-diabetic drugs, led to better control glucose levels and also helped lower of LDL-C levels.

Cites

Effect of Alcoholic Extract of Ziziphora tenuior L on Blood Glucose and Lipid Profiles in Streptozotocin-Induced Diabetic Rats

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APA: Copy

TALEB, A.M., QANNADI, F., CHANGIZI ASHTIYANI, S., ZAREI, A., REZVANFAR, M.R., AKBARI, A., & HEKMATPOU, D.. (2017). THE EFFECT OF AQUEOUS EXTRACT THYMUS KOTSCHYANUS BOISS. ET HOHEN ON GLYCEMIC CONTROL AND DYSLIPIDEMIA ASSOCIATED WITH TYPE II DIABETES: A RANDOMIZED CONTROLLED TRIAL. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), 19(4 ), 234-243. SID. https://sid.ir/paper/27441/en

Vancouver: Copy

TALEB A.M., QANNADI F., CHANGIZI ASHTIYANI S., ZAREI A., REZVANFAR M.R., AKBARI A., HEKMATPOU D.. THE EFFECT OF AQUEOUS EXTRACT THYMUS KOTSCHYANUS BOISS. ET HOHEN ON GLYCEMIC CONTROL AND DYSLIPIDEMIA ASSOCIATED WITH TYPE II DIABETES: A RANDOMIZED CONTROLLED TRIAL. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM)[Internet]. 2017;19(4 ):234-243. Available from: https://sid.ir/paper/27441/en

IEEE: Copy

A.M. TALEB, F. QANNADI, S. CHANGIZI ASHTIYANI, A. ZAREI, M.R. REZVANFAR, A. AKBARI, and D. HEKMATPOU, “THE EFFECT OF AQUEOUS EXTRACT THYMUS KOTSCHYANUS BOISS. ET HOHEN ON GLYCEMIC CONTROL AND DYSLIPIDEMIA ASSOCIATED WITH TYPE II DIABETES: A RANDOMIZED CONTROLLED TRIAL,” IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), vol. 19, no. 4 , pp. 234–243, 2017, [Online]. Available: https://sid.ir/paper/27441/en

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