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Information Journal Paper

Title

THE EFFECT OF SHARK'S CARTILAGE EXTRACT ON LYMPHOCYTE PROLIFERATION OF BREAST CANCER PATIENTS

Pages

  53-60

Abstract

 Introduction: SHARK CARTILAGE has antiangiogenic and immunostimulatory activity, which inhibits tumor growth. There is little scientific evidence about the effect of SHARK CARTILAGE on human immune system. Therefore, in this study we investigated the effect of SHARK CARTILAGE on lymphocyte proliferation and IFNγ production in BREAST CANCER patients.Materials and Methods: After preparing of SHARK CARTILAGE powder and its distribution in capsules, the drug packages were coded. Test-group patients used SHARK CARTILAGE capsules but the control group consumed the starch capsules according to the protocol, they received hormone therapy as well.Blood sampling was done before and after treatment period. After isolating and culturing PBMCs, MTT assay was done and supernatant was collected for measuring the amount of IFNγ by ELISA.Results: The findings indicated that enhancing the treatment period in the test-group would increase the lymphocyte proliferation and IFNγ quantity; however, no significant difference was found for the control group compared to before incorporating the treatment.Conclusion: SHARK CARTILAGE extract stimulates lymphocyte proliferation and IFNγ secretion which will improve the body's defense against tumor.

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    APA: Copy

    SHAHROKHI, S., MOHAMMAD HASAN, ZOHEYR, GHAZANFARI, T., MOHAGHEGHI, S.M.A., & SHAHABI, SH.. (2006). THE EFFECT OF SHARK'S CARTILAGE EXTRACT ON LYMPHOCYTE PROLIFERATION OF BREAST CANCER PATIENTS. DANESHVAR MEDICINE, 13(63), 53-60. SID. https://sid.ir/paper/30892/en

    Vancouver: Copy

    SHAHROKHI S., MOHAMMAD HASAN ZOHEYR, GHAZANFARI T., MOHAGHEGHI S.M.A., SHAHABI SH.. THE EFFECT OF SHARK'S CARTILAGE EXTRACT ON LYMPHOCYTE PROLIFERATION OF BREAST CANCER PATIENTS. DANESHVAR MEDICINE[Internet]. 2006;13(63):53-60. Available from: https://sid.ir/paper/30892/en

    IEEE: Copy

    S. SHAHROKHI, ZOHEYR MOHAMMAD HASAN, T. GHAZANFARI, S.M.A. MOHAGHEGHI, and SH. SHAHABI, “THE EFFECT OF SHARK'S CARTILAGE EXTRACT ON LYMPHOCYTE PROLIFERATION OF BREAST CANCER PATIENTS,” DANESHVAR MEDICINE, vol. 13, no. 63, pp. 53–60, 2006, [Online]. Available: https://sid.ir/paper/30892/en

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