The in vitro survey of cytotoxic activities extracts of garlic and green tea

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SHARIFZADEH ALI; Aali Faranak; Heidari Milad; Kowsari Neda

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Journal: Feyz Medical Sciences Journal Year:2020 | Volume:24 | Issue:3 Page(s): 342-349

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Title

The in vitro survey of cytotoxic activities extracts of garlic and green tea

Author(s)

SHARIFZADEH ALI | Aali Faranak | Heidari Milad | Kowsari Neda | Issue Writer Certificate

Keywords

GarlicQ3

Green teaQ2

Breast cancerQ1

CytotoxicityQ2

Abstract

Background: Garlic (Allium sativum) belongs to the Liliaceae family and Green tea (Camellia sinensis) belongs to the Theaceae family are widely used in folk medicine. Antibacterial, anticancer and antioxidant activity of these plants have been previously reported. This study aimed to investigate the cytotoxic activity of the extracts of Garlic and Green tea on breath cancer cell line (MCF-7) and HDF. Materials and Methods: Cytotoxicity of different concentrations (250, 500, 750 μ g/ml) of Garlic and Green tea ethanolic extracts on MCF-7 and HDF cell lines were examined. The cell lines were grown in RPMI supplemented with 10% FBS, 1% penicillin and streptomycin. The cells were allowed to incubate at 37º C in an atmosphere that contained 5% CO2 and 95% humidity. The standard MTT assay was performed to estimate cell viability after treatment Garlic and Green tea extracts. Results: The results of the MTT assay showed that Garlic extract had time and concentration dependent anticancer activities on the MCF-7 cell line (P<0. 01). But, any effect of Green tea extract on MCF-7 and HDF cell lines showed. Conclusion: Results of this survey suggested that Garlic extract has a good potential to control of cancer cells.

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APA: Copy

SHARIFZADEH, ALI, Aali, Faranak, Heidari, Milad, & Kowsari, Neda. (2020). The in vitro survey of cytotoxic activities extracts of garlic and green tea. FEYZ, 24(3 ), 342-349. SID. https://sid.ir/paper/366895/en

Vancouver: Copy

SHARIFZADEH ALI, Aali Faranak, Heidari Milad, Kowsari Neda. The in vitro survey of cytotoxic activities extracts of garlic and green tea. FEYZ[Internet]. 2020;24(3 ):342-349. Available from: https://sid.ir/paper/366895/en

IEEE: Copy

ALI SHARIFZADEH, Faranak Aali, Milad Heidari, and Neda Kowsari, “The in vitro survey of cytotoxic activities extracts of garlic and green tea,” FEYZ, vol. 24, no. 3 , pp. 342–349, 2020, [Online]. Available: https://sid.ir/paper/366895/en

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