EFFECTS OF BLACKBERRY (MORUS NIGRA L.) CONSUMPTION ON SERUM CONCENTRATION OF LIPOPROTEINS, APO A-I, APO B, AND HIGH-SENSITIVITY-C-REACTIVE PROTEIN AND BLOOD PRESSURE IN DYSLIPIDEMIC PATIENTS

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KESHTKAR AGHABABAEE SAHAR; VAFA MOHAMMAD REZA; SHIDFAR FARZAD; TAHAVORGAR ATEFEH; GOHARI MAHMOUD REZA; KATEBI DAVOD; MOHAMMADI VIDA

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Journal: JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS) Year:2015 | Volume:20 | Issue:7 Page(s): 685-692

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Title

EFFECTS OF BLACKBERRY (MORUS NIGRA L.) CONSUMPTION ON SERUM CONCENTRATION OF LIPOPROTEINS, APO A-I, APO B, AND HIGH-SENSITIVITY-C-REACTIVE PROTEIN AND BLOOD PRESSURE IN DYSLIPIDEMIC PATIENTS

Author(s)

Keywords

APOLIPOPROTEINS

BLACKBERRY

BLOOD PRESSURE

HIGH-SENSITIVITY-C-REACTIVE PROTEIN

Abstract

Background: This study investigated BLACKBERRY (Persian mulberry) effects on apo A-I, apo B, HIGH-SENSITIVITY-C-REACTIVE PROTEIN (hs-CRP), and systolic BLOOD PRESSURE (SBP) and diastolic BLOOD PRESSURE (DBP) in dyslipidemic patients.Materials and Methods: In this 8-week randomized clinical trial, 72 dyslipidemic patients were randomly divided into two groups: Intervention (300 mL/day BLACKBERRY juice with pulp) and control group (usual diets). Before and after the intervention, fasting blood samples were taken from both groups and serum concentration of lipoprotein, apo A-I and apo B, serum lipids (total cholesterol, low-density lipoprotein, highdensity lipoprotein [HDL], and triglyceride), hs-CRP were measured. BLOOD PRESSURE before and after the study was measured with a mercury manometer. Results: At week 8 in the intervention group, apo A-I and HDL increased significantly (P = 0.015, P = 0.001, respectively), apo B and hs-CRP decreased significantly (P = 0.044, P = 0.04, respectively). Mean changes in apo A-I and HDL and apo B/apo A-I ratio were significant between the groups (P = 0.005, P = 0.014, and P = 0.009, respectively). After 8 weeks, there was a significant difference between hs-CRP mean values (P = 0.01) of the groups. At week 8, SBP decreased significantly (P = 0.005) in the intervention group with no significant differences for SBP mean values between the groups. No significant changes were observed in other lipid parameters and DBP in the intervention group and between the groups. Conclusion: BLACKBERRY consumption may exert beneficial effects on APOLIPOPROTEINS, BLOOD PRESSURE, and inflammatory markers in individuals with lipid disorders.

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APA: Copy

KESHTKAR AGHABABAEE, SAHAR, VAFA, MOHAMMAD REZA, SHIDFAR, FARZAD, TAHAVORGAR, ATEFEH, GOHARI, MAHMOUD REZA, KATEBI, DAVOD, & MOHAMMADI, VIDA. (2015). EFFECTS OF BLACKBERRY (MORUS NIGRA L.) CONSUMPTION ON SERUM CONCENTRATION OF LIPOPROTEINS, APO A-I, APO B, AND HIGH-SENSITIVITY-C-REACTIVE PROTEIN AND BLOOD PRESSURE IN DYSLIPIDEMIC PATIENTS. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), 20(7), 685-692. SID. https://sid.ir/paper/667811/en

Vancouver: Copy

KESHTKAR AGHABABAEE SAHAR, VAFA MOHAMMAD REZA, SHIDFAR FARZAD, TAHAVORGAR ATEFEH, GOHARI MAHMOUD REZA, KATEBI DAVOD, MOHAMMADI VIDA. EFFECTS OF BLACKBERRY (MORUS NIGRA L.) CONSUMPTION ON SERUM CONCENTRATION OF LIPOPROTEINS, APO A-I, APO B, AND HIGH-SENSITIVITY-C-REACTIVE PROTEIN AND BLOOD PRESSURE IN DYSLIPIDEMIC PATIENTS. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS)[Internet]. 2015;20(7):685-692. Available from: https://sid.ir/paper/667811/en

IEEE: Copy

SAHAR KESHTKAR AGHABABAEE, MOHAMMAD REZA VAFA, FARZAD SHIDFAR, ATEFEH TAHAVORGAR, MAHMOUD REZA GOHARI, DAVOD KATEBI, and VIDA MOHAMMADI, “EFFECTS OF BLACKBERRY (MORUS NIGRA L.) CONSUMPTION ON SERUM CONCENTRATION OF LIPOPROTEINS, APO A-I, APO B, AND HIGH-SENSITIVITY-C-REACTIVE PROTEIN AND BLOOD PRESSURE IN DYSLIPIDEMIC PATIENTS,” JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), vol. 20, no. 7, pp. 685–692, 2015, [Online]. Available: https://sid.ir/paper/667811/en

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