EFFECT OF GALLIC ACID ON PASSIVE AVOIDANCE MEMORY UNDER BRAIN ISCHEMIA CONDITIONS IN MATURE FEMALE RATS

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RAHIMI ASL F.; FARBOOD Y.; SARKAKI A.R.; HOSSEINI S.E.

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Journal: Internal Medicine Today Year:2014 | Volume:20 | Issue:1 Page(s): 23-27

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Title

EFFECT OF GALLIC ACID ON PASSIVE AVOIDANCE MEMORY UNDER BRAIN ISCHEMIA CONDITIONS IN MATURE FEMALE RATS

Author(s)

RAHIMI ASL F. | FARBOOD Y. | SARKAKI A.R. | HOSSEINI S.E. | Issue Writer Certificate

Keywords

CEREBRAL ISCHEMIAQ2

MEMORYQ2

GALLIC ACIDQ2

RATQ2

Abstract

Aims: CEREBRAL ISCHEMIA is a condition that to the all or parts of the brain does not reach blood and as a result enough oxygen. Due to the debilitating effects of CEREBRAL ISCHEMIA, this study was done to investigate the effect of GALLIC ACID on passive avoidance MEMORY in adult female RATs under bilateral CEREBRAL ISCHEMIA condition.Methods: 84 RATs were randomly divided into 6 control (C; without any manipulation of carotid artery and treatment), GALLIC ACID control (CGA; without any manipulation of carotid artery and treated with GALLIC ACID), ischemia control (CI; manipulated with carotid artery but not occlusion and without treatment), ischemia (I; complete and bilateral occlusion of carotid arteries and without treatment), solvent ischemia (IS; complete and bilateral occlusion of carotid arteries with normal saline gavage) and GALLIC ACID ischemia (IGA; complete and bilateral occlusion of carotid arteries with GALLIC ACID gavage) groups each had 14 RATs. The shuttle box was used to investigate the passive avoidance learning behavior. Data were analyzed using One-way ANOVA and LSD logistic tests.Results: After the application of electric shocks, the STL time in each of the I and IS groups had significant reduction compared to CI group and in IGA group increased significantly compared to I group.72 hours after application of electric shock, the STL time in CGA group had a significant increase compared to the CI group and 7 days after the application of electric shock the STL time in IGA group had a significant decrease compared to CI group.Conclusion: GALLIC ACID increases the passive avoidance MEMORY in RATs with CEREBRAL ISCHEMIA.

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APA: Copy

RAHIMI ASL, F., FARBOOD, Y., SARKAKI, A.R., & HOSSEINI, S.E.. (2014). EFFECT OF GALLIC ACID ON PASSIVE AVOIDANCE MEMORY UNDER BRAIN ISCHEMIA CONDITIONS IN MATURE FEMALE RATS. OFOGH-E-DANESH, 20(1), 23-27. SID. https://sid.ir/paper/68325/en

Vancouver: Copy

RAHIMI ASL F., FARBOOD Y., SARKAKI A.R., HOSSEINI S.E.. EFFECT OF GALLIC ACID ON PASSIVE AVOIDANCE MEMORY UNDER BRAIN ISCHEMIA CONDITIONS IN MATURE FEMALE RATS. OFOGH-E-DANESH[Internet]. 2014;20(1):23-27. Available from: https://sid.ir/paper/68325/en

IEEE: Copy

F. RAHIMI ASL, Y. FARBOOD, A.R. SARKAKI, and S.E. HOSSEINI, “EFFECT OF GALLIC ACID ON PASSIVE AVOIDANCE MEMORY UNDER BRAIN ISCHEMIA CONDITIONS IN MATURE FEMALE RATS,” OFOGH-E-DANESH, vol. 20, no. 1, pp. 23–27, 2014, [Online]. Available: https://sid.ir/paper/68325/en

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