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Information Journal Paper

Title

Antiglycation and antitumoral activity of Tribulus terrestris dry extract

Author(s)

 Malaguti Figueiredo Celia Cristina | Gomes Amanda Costa | Granero Filipe Oliveira | Bronzel Junior Joao Luiz | Silva Luciana Pereira | Tasca Gois Ruiz Ana Lucia | Goncalves da Silva Regildo Marcio | Issue Writer Certificate 

Pages

  224-237

Abstract

 Objective: Investigation of the antiglycation and antitumoral potential of standardized and saponins-enriched extracts of Tribulus terrestris herbal medicine. Materials and Methods: The procedures for the evaluation of the antiglycation activity of the standardized (TtSE) and saponins-enriched (TtEE) extracts of T. terrestris were: determination of relative mobility in electrophoresis (RME), free amino groups using OPA method and advanced glycation end-products (AGEs) fluorescence. Antioxidant activity was determined by DPPH radical scavenging test. In vitro antitumor activity of TtSE and TtEE was evaluated in human tumor cell lines. Results: The results were obtained by antiglycation tests (RME, OPA method and AGEs fluorescence determination), using BSA as protein and ribose as glycation agent, and antioxidant assay (DPPH test); it was verified that both extracts of T. terrestris have antiglycation and antioxidant activity. In addition, the extracts were able to induce death of more than 50% of human tumor cell lines. Conclusion: The present study showed that standardized and saponins-enriched extracts of T. terrestris herbal medicine present antiglycation and antioxidant and Antiproliferative action in human tumor cells lines. The saponins-enriched extract proved a greater antiglycation and antioxidant activity in comparison to the standardized type.

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    Cite

    APA: Copy

    Malaguti Figueiredo, Celia Cristina, Gomes, Amanda Costa, Granero, Filipe Oliveira, Bronzel Junior, Joao Luiz, Silva, Luciana Pereira, Tasca Gois Ruiz, Ana Lucia, & Goncalves da Silva, Regildo Marcio. (2021). Antiglycation and antitumoral activity of Tribulus terrestris dry extract. AVICENNA JOURNAL OF PHYTOMEDICINE (AJP), 11(3), 224-237. SID. https://sid.ir/paper/690100/en

    Vancouver: Copy

    Malaguti Figueiredo Celia Cristina, Gomes Amanda Costa, Granero Filipe Oliveira, Bronzel Junior Joao Luiz, Silva Luciana Pereira, Tasca Gois Ruiz Ana Lucia, Goncalves da Silva Regildo Marcio. Antiglycation and antitumoral activity of Tribulus terrestris dry extract. AVICENNA JOURNAL OF PHYTOMEDICINE (AJP)[Internet]. 2021;11(3):224-237. Available from: https://sid.ir/paper/690100/en

    IEEE: Copy

    Celia Cristina Malaguti Figueiredo, Amanda Costa Gomes, Filipe Oliveira Granero, Joao Luiz Bronzel Junior, Luciana Pereira Silva, Ana Lucia Tasca Gois Ruiz, and Regildo Marcio Goncalves da Silva, “Antiglycation and antitumoral activity of Tribulus terrestris dry extract,” AVICENNA JOURNAL OF PHYTOMEDICINE (AJP), vol. 11, no. 3, pp. 224–237, 2021, [Online]. Available: https://sid.ir/paper/690100/en

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