THE EFFECT OF ORAL LECITHIN ON SPATIAL LEARNING OF ADULT MALE RATS

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AFARINESH M.; MOAZEDI A.A.; ABBASNEZHAD M.

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Journal: JOURNAL OF RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES Year:2004 | Volume:3 | Issue:3 Page(s): 141-148

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Title

THE EFFECT OF ORAL LECITHIN ON SPATIAL LEARNING OF ADULT MALE RATS

Author(s)

AFARINESH M. | MOAZEDI A.A. | ABBASNEZHAD M. | Issue Writer Certificate

Keywords

LECITHINQ3

SPATIAL LEARNINGQ3

RATQ2

T-MAZE- FIGUREQ4

Abstract

Background: LECITHIN (phosphatidylcholine) is known as a precursor of acetyl chorine. The studies on experimental animals, have shown that the cholinergic system has an important role in learning and memory. Therefore, in this study we investigated the effects of different doses of LECITHIN on the SPATIAL LEARNING. Materials and Methods: The adult male NMRI RATs (250± 25 g and 4.5-5 months) were used. All animals were trained for a SPATIAL LEARNING task using T-maze and were trained for subsequently nine days based on standard method (n=7). Animals were divided into 5 groups as follows: LECITHIN (480,240,120 IU/kg) 0.1ml/10g B.W was administrated for 9 days subsequently in groups 1-3, one hour before each day the experiments. LECITHIN's sham group (group 4) received distilled water by gavaged, and the control group (group 5) received normal food.Results: Statistical analysis, ANOVA, has shown that LECITHIN, in all three doses, decreased the mean of running times (p<0.05, p<0.001, p<0.001), but it had no significant effect on the number of errors. Conclusion: It seems LECITHIN increase acetyl chorine, which in turn improves the function of cholinergic system in hippocampus.

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APA: Copy

AFARINESH, M., MOAZEDI, A.A., & ABBASNEZHAD, M.. (2004). THE EFFECT OF ORAL LECITHIN ON SPATIAL LEARNING OF ADULT MALE RATS. JOURNAL OF RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES, 3(3), 141-148. SID. https://sid.ir/paper/71351/en

Vancouver: Copy

AFARINESH M., MOAZEDI A.A., ABBASNEZHAD M.. THE EFFECT OF ORAL LECITHIN ON SPATIAL LEARNING OF ADULT MALE RATS. JOURNAL OF RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES[Internet]. 2004;3(3):141-148. Available from: https://sid.ir/paper/71351/en

IEEE: Copy

M. AFARINESH, A.A. MOAZEDI, and M. ABBASNEZHAD, “THE EFFECT OF ORAL LECITHIN ON SPATIAL LEARNING OF ADULT MALE RATS,” JOURNAL OF RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES, vol. 3, no. 3, pp. 141–148, 2004, [Online]. Available: https://sid.ir/paper/71351/en

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