JOURNAL OF RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES
Year:2020 | Volume:19 | Issue:6|Papers Count:9

Background and Objectives: kidney diseases threaten mental and physical health. Acceptance and commitment therapy is a third generation treatment that affects life quality of patients. The present research aimed at determining the effect of acceptance and commitment based therapy on life quality of homodialized and kidney transplant patients in Zanjan city. Materials and Methods: This was a randomized clinical trial study. Statistics of the research includes all homodialized and kidney transplant patients admitted in kidney patients association in 2017. Eighty out of them were chosen and randomly grouped in control (two) and experimental (two) groups. The experimental group of acceptance and commitment based therapy were treated for 8 sessions (a 1. 5 hour session per week) and the control groups received no intervention. Posttest was accomplished in both groups at end of the experiment. Data were analyzed using multiple analysis of covariance (MANCOVA) and one-way analysis of covariance (ANCOVA). Results: : Mean and standard deviation of the experimental group age was 41. 95± 8. 98 and 10. 39± 8. 89 years for kidney transplantation and hemodialyzed groups, respectively and in the control group 42. 20± 9. 12 and 45. 35± 6. 47 years for kidney transplantation and hemodialyzed groups, respectively (p=0. 148). There was a significant differencein life quality and its dimensions including mental health and perception of life environment between kidney transplantation and hemodialysis groups (p<0. 001) Conclusion: According to the findings, using acceptance and commitment based therapy is suggested as an effective and complementary psychological intervention in kidney and homodialyzed patients to improve their life quality.

Background and Objectives: The stress caused by maternal separation in the early days after birth induces autistic behaviors. Hypericin has many biological properties, including antidepressant and anti-inflammation. Therefore, this study aimed at determining hypericin effect on autism behaviors that induced by maternal separation model. Materials and Methods: In this experimental study, Wistar rats were divided into two control and maternal separation groups. The rats in the maternal separation group were subjected to individual separation from their mother for 1 h per day (postnatal day1-9). The maternal separation group was divided into 4 subgroups: Autism, fluoxetine, hypericin (10mg/kg), hypericin (50mg/kg). Treatment was gavaged in pups on postnatal day 21-34. In the end of day 34, neurobehavioral tests (grooming, social interaction and open field test) were carried out. Statistical analysis and between group comparison were performed using one-way ANOVA followed by Tukey's test. Results: In the pups subjected to individual isolations from their mother, social deficits (p=0. 007), excessive repetitive behavior (p=0. 001), and anxiety (p=0. 001) were increased. Whereas, hypericin could reduce repetitive behaviors index (p=0. 011), anxiety (p=0. 001) and social interaction deficits (p=0. 031) in the maternal isolation autism rat model. Conclusion: These findings indicated that maternal separation may produce autistic-like behaviors, and hypericin through antidepressant effect may be a potential therapeutic agent against autistic-like behavior.

Background and Objectives: Training patients before surgery can reduce postoperative pain and anxiety. This study aimed to compare the effect of face to face education and video training on the anxiety of patients requesting bone marrow transplantation. Materials and Methods: This randomized clinical trial study was performed over a period of 9 months in the bone marrow transplant ward of Afzalipour hospital affiliated to Kerman University of Medical Sciences (KMU) in 2018. The sampling method was convenience. 34 cases were assigned to each of two groups. Face-to-face training was conducted in three sessions, each session 40 minutes one week before admission. In the video training, the video of treatment and transplantation was given to the patient one week before admission. In both groups, patients' anxiety levels were examined before and after training. Demographic questionnaire and State-Trait Anxiety Inventory (STAI) were used for data collection and people completed the questionnaires independently. Independent samples t-test, paired sample t-test, Chi-square test and Fisher's exact test were used to analyze the data. Results: The mean score of patients' anxiety in the face-to-face training group decreased 25. 32± 12. 54 score after the educational intervention (p=0. 001). The mean score of patients' anxiety in the video training group also decreased 24. 94± 16. 77 score after the educational intervention (p=0. 001). There was no significant difference between face-to-face education and video training group (p=0. 921). Conclusion: The results of this study showed that face-to-face and video-based educational interventions can reduce the level of anxiety in transplant patients. Therefore, according to the patient's condition, one of the training methods can be selected.

Background and Objectives: Sick building syndrome (SBS) is a building-related illness in which people in the environment do not experience proper physical and mental well-being. Mental and physical changes include headache, nausea, abnormal fatigue, lack of concentration, sensation of an unpleasant odor. Thus, the aim of this study was to investigate the frequency of SBS and its related factors in nurses at Ali Ibn Abitaleb hospital in Rafsanjan City in 2018. Materials and Methods: This cross-sectional study was performed using standard MM040EA questionnaire related to SBS and indoor air quality at Ali Ibn Abitaleb hospital in Rafsanjan city in 2018. 285 nurses in different wards of the hospital were entered the study using census method. Data were analyzed by descriptive statistics and chi-square test. Results: The mean ± standard deviation of age for participating nurses was 34. 04± 7. 90 years. Fatigue 88 (63. 8%), dry hands and itching and red skin 71 (51. 4%) were the most frequent symptoms of SBS among the nurses. 68 (49. 3%) nurses complained of unpleasant odors of the workplace every week, and 77 (56. 2%) nurses felt their workload was sometimes high. Demographic characteristics, work environment and working conditions did not show any statistically significant difference with the frequency of SBS (p>0. 05). Conclusion: Due to the high frequency of SBS in hospital nurses and its effects on performance and productivity, it is necessary to re-engineer the hospital environment and improve the work environment, especially ventilation of hospital wards.

Background and Objectives: Low birth weight is one of the most widespread public health problems associated with high infant mortality. This study aimed to identify maternal risk factors affecting low birth weight neonates in Rafsanjan hospitals. Materials and Methods: This case-control study consisted of 120 low birth weight infants (less than 2500 grams) as the case group and 120 normal weight infants (2500 grams and more) as controls in 2018. The data were collected by a randomized checklist from the records of the delivery mothers in the hospitals of Rafsanjan and were analyzed using Chisquare, independent t-test and logistic regression. Results: According to the results of the tests, the number of prenatal care and gestational age at birth was lower in the case group than in the control group, but the history of low birth weight was higher in the case group. Logistic regression for the history of low birth weight (OR=4. 196, p=0. 008) in the case group was more than the control and mean birth interval (OR=0. 992, p=0. 036) and gestational age at birth delivery (p<0. 001, OR=0. 61) was lower in the case group than in the control group. Conclusion: Findings showed that low number of prenatal care, having low birth weight, preterm delivery, and low birth interval have a role in low birth weight. Therefore, increasing pregnancy care coverage and paying attention to mothers who have low birth weight and preterm birth and increasing the interval between births can decrease low birth weight infants.

Background and Objectives: Mitochondrial creatine kinase involves in UCP-independent thermogenesis. It isthought that the agent can be affected by nutrition and exercise. The aim of this study was to investigate the longterm effect of high fat diet and regular aerobic exercise training on gene expression of mitochondrial creatine kinase 1 (CKmt1) and mitochondrial creatine kinase 2 (CKmt2) in white adipose tissue of mice. Materials and Methods: In this experimental study, 28 male C57BL/6 mice were divide into four groups including control (n=7), high fat diet (HFD) (n=7), exercise training (ET) (n=7) and HFD-exercise training (HFD-ET) (n=7). The subjects of the HFD groups were fed a high-fat diet (fat: %40) for a period of 12 weeks. The subjects of the training groups underwent continuous training for six weeks. The Real Time– PCR method was used to measure the expression levels of the Ckmt1and Ckmt2 genes. The two-way ANOVA was applied to analyze data. Results: Data showed that the HFD (p=0. 324) and ET (p=0. 136) did not significantly affect the gene expression level of CKmt1. However, the gene expression level of CKmt2 was significantly decreased and increased by HFD and ET versus high fat diet group, respectively (p=0. 043; p=0. 001, respectively). Conclusion: The findings of this study indicated that the long term feeding of high fat diet and regular aerobic training could probably affect the non-shivering thermogenesis at white adipose tissue by decreasing and increasing the expression of mitochondrial creatine kinase 2 (CKmt2), respectively.

Background and Objectives: Reducing patients' anxiety is one of the medical team’ s duties. The present study aimed to determine the relationship between waiting time before surgery and patients' anxiety. Materials and Methods: This descriptive study was conducted in educational and medical centers of Kurdistan in 1398. Spielberger Anxiety Assessment Questionnaire was used to collect data. Independent t-test, Pearson’ s correlation coefficient and one-way analysis of variance were used to analyze the data. Results: The mean of apparent and hidden anxiety of patients at the time of entering the waiting room was 45. 55 (8. 35) and 43. 97 (8. 07), respectively. At the time of departure, it was 47. 32 (8. 81) and 46. 17 (8. 84), respectively. Which showed moderate to high anxiety in patients. There was a direct relationship between the waiting time before surgery and the anxiety score (p<0. 05). Conclusion: The results showed the anxiety of all research samples before surgery and there was a significant statistical relationship between the time before surgery and patients' anxiety.