Yafteh
Year:2002 | Volume:3 | Issue:11|Papers Count:12

HLA Molecules are the principal agents for recognition of foreign antigens. Also the correlation of these molecules is established with different diseases. The present research, is a descriptive study and was done in order to determine the frequency of class I and II HLA molecules in normal population of Khoramabad in 2001 by using standard. method of lymphocytotoxicity.Determination of frequency of class I HLA molecules in 50 normal individuals was shown in locus A, the most frequency belonged to Al and All antigens that with comparison between Iranian normal population and Khoramabad normal population showed that frequency of these antigens are higher in Khoramabad normal population and this difference was statistically significant. In locus B the most frequency of class I HLA belonged to B5 and B7 which in comparison with Iran normal population was higher. The most and the lowest frequency in locus C belonged to CW4 and CW1, CW2 sequentially.Distribution of CW4 and CW5 antigens were higher in normal population of Khoramabad, in comparison with Iran normal population.Also, the results from determination of frequency of class II HLA antigens in 43 normal individuals showed that DR53 and DR7 in locus DR have higher frequency, but in Iran normal population, DR53 has higher frequency.Distribution of DQ1, DQ2 and DQ3 antigens in locus DQ nearly was same, distribution of HLA-DQ2 Antigen was higher in Khoramabad normal population in comparison with normal population of Iran.

Many researches have been carried out on opioids analgesic efficacy. Some reports showed intra-articular opioids to be ineffective, others reported a significan positive effect on postoperative analgesia. We evaluated the efficacy of intra-articular Sufentanil in the prevention of postoperative pain after diagnostic knee arthroscopic procedures .Sixty patients were randomly assigned to receive either intra articular Sufentanil 7.5 mg and saline IV(group A),or intra articular saline and sufentanil 7.5 mg/IV (group B=Control).Study was double blinded. At postoperation and day after surgery, pain levels at rest and during movment (i.e, active flexion of the knee), measured by a visual analog scale, were significantly lower in the group A .Morever, intra articular Sufentanil significantly reduced the postoperative consumption of analgesics. The time until discharge from the postoperative care unit was significantly shorter in the patients receiving Sufentanil intra-articularly. So we conclude that intra atricular Sufentanil in arthroscopic knee procedures is a simple, effective, safe and well-tolerated analgesic technique for outpatients undergoing arthroscopic procedures.

Hypericum perforatum is on of the members of Hypericaciea family and from long time ago it had been used for treatment of many diseases such as hair and skin lesions, children anureses, depression and mental disorders. Nowadays in many countries including Germany it is used frequently in making soft drinks and a ariety of drugs have been drived from it in the form of tablet, ointment, syrup and etc.The aim of this study was to assess the genotoxicity effects of alcohol extract of the plant.Aines test along with two strains of Salmonella typhymorium TA98 ,TA100, because of their high sensitivity, were chosen to carry out this research. At first the two strains checked from view point of existence or lack of mutations and additional plasmids of rfa,uvrb,PKM101,then alcohole extract obtained from dry top branches and both the strains were cultured in minimum glucose agar culture and exposed at different volumes of 10,20,50,100,200,250 and 300 microliters and hen created clonies were counted after 48 hours in condition of 37°C.Regarding the criteria of evaluation, the alcohol extract of Hypericum perforatum using two bacterial strains of TA98, TA100 and by use of Ames is not mutagen.

depression is one of the most Prevalent mental disorders in the world. According to the joint report of WHO and world bank, mood disorders rank first among the ten most Important causes disability and disablement in the world.this study was carried out to determine the prevalence of depression in thehran. 1191 tehranian individuals including 585 females and 606 males aged 20-40 sample size and studied using beck depression test and clinical interview based on DSM-IV  diagnostic criteria.Results showed that the prevalence rate of depression was 22.5% this rate was 29.2% in females and 16% in males, the difference was significant statistically. The prevalence rate of major depression during one month was 6.7% (10.1% in females and 3.5% in males). 0.5% of the samples suffered from dysthvmic disorder. In this study a significant relationship observed between variables of literacy level, marital status, employment status, and prevalence of depression, but there was not significant relationship observed between variables of literacy level, marital status, employment status, and prevalence of depression.significant relationship between age and prevalence of depression.regarding the high prevalence of depression, revision in medical education and promotion of psychiatry education level for general physicians sound necessary. increase of social knowledge throught the media for reference and treatment and conswquently reduce of socio-economic burden of these disorders cant be denied as well.

One of the effective parameters on the water chlorination efficiency is water turbidity, so that high turbidity decreases chlor effect on bacteria.This descriptive study covered all springs that supply Khoramabad drinking water. Sampls collected from springs weekly before and after chlorination in the form of triplicate samples series, one before chlorination and three times triplicate series after the chlorination. Using thiusolphalt sodium, the chlor of the first series samples was removed immediately, and the chlor of the second and thired series were removed 15 and 30 minutes afterwards respectively.Samples for total coliforms E.coli and turbidity tests were sent to laboratory very fast (less than 2 hours).Results showed that tap water turbidity increased in the end of Isfand and Farvardin. So turbidity content is higher than WHO guidelines. This increase of turbidity correlates with chlorination efficiency (Immediately after chlorination) So it results in increasing of total coliform becteria and E.coli, but with pass of time of the chlorination this correlation is lost and no significant relation is observed between chlorination efficiency and turbidity.So it is recommended to avoid of direct injection of springs' water to the distribution system immediately after chlorination, and to be remain in the supply sources for at least 15 minutes.

Acne is a chronic inflammatory disorder of the pilosebaceous follicles which starts in adolescence and resolves by about twenties. Acne vulgaris is a common dermatological problem which is observed in patients with polycystic ovaries too.This descriptive study was carried out on 80 patients with severe acne. The purpose of the study was to determine the frequency of polycystic ovaries in the patients referred to specialized clinic of shahid Rahimi hospital in Khoramabad from Aug ,1999 to jully, 2000 according their ultrasonography. Results and findings showed that out of 80 patients with severe acne, fifty cases (62.5%) had PCO on altrasonography .The maximum frequency was in the age group of 20-24 years old (46.3%) and 45% of the patients had oligomenorrhea, 3.7% had infertility, 45% had family history of acne. Most of the patients complained of premenestural flare of acne.According to the findings it is better, for theses patients, to do ultrasonograply of ovaries before starting treatment.

The first reference for admission for admission of ME clients is emergency ward. Regarding that ME is one of the priorities of health system research in the country, this descriptive cross sectional study was carried out for epidemiologic evaluation of ME-hospilalized patients in Khorramabad shahid Rahimi hospital during one year (2000).Sample size was 1220 HP that were 50 percent of the total HP in study period. A questionnaire used for data collection with observation, interview and using medical records.The results showed that of 1220 subjects, 57.8% were males, and age of 36.5% was 50-59 years old. 81.5% were married, 15.5% were referred by stretcher, 30.5% were referred in autumn. 79.5% were allert on admission 40.4% had cardia vascular emergency and 1.8% had died. The hospital cost for 12% was free. The mean of expense was 460540 RIs, and EKG was the most common taken measure. The correlation between reference causes and age, expense, marital status sex; and death with PV=0.00 was significant .We suggest doing more studies as well as, those who are in charg of health and treatment services should provide and find pricipal strategies to offer optional services to EM clients in EM centers.

Diarrhea in children is among the main causes of mortality, malnutrition and mental and physical retardation.The aim of this study is isolation and identification of bacterial agents causing acute diarrhea in children under ten years old and also detection of serotypes of the isolates. This study is a descriptive cross-.sectional investigation.During a period of 2 years (From Nov, 1998 to Sep, 2000),544 feces specimens were collected from children under ten years old with acute diarrhea. In order to isolate strians, the samples were cultured on selenite F,SS agar and E.M.B agar for isolation of the Salmonella and Shigella species and on CIN agar, PBS for isolation of Yersinia species. The isolates were examined to detection of serotypes polyvalent and monovalant specific antisera Of 544 samples, 134 isolates (24.6%) were identified as pathogen bacteria including EPEC 88 isolates (65.8%), Shigella 26 isolates (19.5%), Salmonella 13 isolates (19.5%) and Yersinia enterocolitica 7 isolates (5.2%). The most frequent serotypes were E.Coli 055 (38.6%) followed by shigella flexneri (26.8%) and, Salmonella para B and typhi 30.8% for each one. Results showed that identification of bacterial agents causing children diarrhea in different geographic regions is necessary and isolation of new species by use of modem techniques is suggested.

Health volunteers (Rabeteen Behdshti) are the pioneers of a public cooperation that have voluntarily taken steps on the road of public participation for security and promotion the level of social health. Based on studies these devoted people have stopped their cooperation for different reasons .Therefore considering the problems of this group can prevent the discontinuation of their cooperation.This analytic -descriptive study was carried out to determine the problems of the health volunteers of Lorestan health centers in 2000.In this study 491 out of 1813 individuals with accuracy of %4 were selected randomly. Data was collected using a two - part questionnaire including individual information and basic questions about their problems.According to the findings problems of the health volunteers were of different types ,so that socio economical problems with X=4.62 acquired first priority in comparison with others, then centers problems (X=4.34), cultural (X=3.7), Communicating problems (X=3.72), educational and justification problems (X=2.33) and family problems (X=0.43). There were significant difference between their average score and educational levels of their spouses (P=0.01), between their marital status and communicative difficulties (P=0.02) with their jobs and the average of the connectives problems (P=0.03) and income with their socio ecconomic problems has, that can result in breaking off their cooperation. Regarding the results of this study and paying attention to the necessity of public cooperation, the importance of the Health volunteers role, the need for increasing their motivation, solving their problems sound necessary.

SCC is one of the most common non melanoma tumors. Arsnic in old wells are regions of poor hygienic condition are among common causing factors of it. In the study a man and his wife both with ehronic arsnism, detected by hair and nail test afllicted with SCC.Radioactive test demonstrated the existence of Arsnism in their hairs and nails.