The concept of organizational performance over the past two decades has been at the center of developments in public administration and has become a major goal. Information and communication technology, the increasing prosperity, and large impacts on all facets of society, including labor and employment, have led to the phenomenon of teleworking (i.e. the work done at a distance). On the other hand, human resources, quality of life and burnout are among the most important issues that impact organizational performance and the trend toward telecommuting. In this research, using a descriptive method, a model is provided to evaluate various aspects of teleworking, organizational performance, burnout and quality of life as well as to consider their impacts on organizational performance. The study involved all the employees of the government agencies in Yazd including 3, 000 people. As many as 342 were selected from the whole initial population using a simple random sampling method. To analyze the data, structural equation modeling is used. The results of the data analysis show that there is a significant relationship between quality of life and organizational performance, between teleworking and organizational performance, between burnout and organizational performance, and between burnout and teleworking period at the coefficients of 0.584, 0.369, 0.281, and 0.572 respectively. However, quality of life and teleworking are found to be correlated not significantly; the correlation coefficient is 0.102. The results also suggest that, with regard to quality of life and burnout, providing conditions for telework can increase organizational performance.