DANESHVAR MEDICINE
Year:2008 | Volume:15 | Issue:73|Papers Count:13

Introduction: The aim of this study was to determine the effect of the different aspects of sexuality, communication and conflict resolution counseling on the marital satisfaction.Materials & Methods: This was an interventional study. A sample of 60 couples that their duration of marriage was 1 to 5 years ago participated during 10 hours through 5 sessions of counseling. Standard Enrich question or was used at 3 phases, pretest before counseling, post test and follow up 4 weeks and 6 months after counseling.Results: The results showed that the difference of mean marital satisfaction in pretest & post test, pretest & follow up, post test & Follow up was significant (p<0.0001) and the mean in follow up was more than post test and post test was more than pretest.Conclusions: According to this marriage counseling enhances the relationship of marriage that increase marital satisfaction and lead to marital stability.

Introduction: Diarrhea diseases are one of the leading causes of morbidity and mortality worldwide. In some countries, children less than five years have diarrhea for 15% days of their life.Objective: Effectiveness of aqueous garlic extract against inflammatory gastroenteritis.Material & Method: This is a clinical trial study and children 2-10 years old who have inflammatory gastroenteritis entered in this study. Sampling method has been randomized block design. Twenty patients were cases and twenty patients were control group. Two groups have same treatment protocol only in using garlic 20 mg/kg/day bid for five days in case group.Results: Aqueous garlic extract can reduce frequency of diarrhea meaningfully after 2nd day. There is meaningful difference about fever in 2nd day between two groups. There is meaningful difference about leukocyte in stool in 4th day between two groups. There is no meaningful difference about nausea and vomiting.Conclusion: we found out that garlic decreases fever, frequency and duration of diarrhea, leukocyte in stool and appetite fast. So aqueous garlic extract is effective herbal drug in inflammatory gastroenteritis.

Objective: The objective of this study was a clinical and radiographic evaluation of Neo-Os particles in bone regeneration in the distal of mandibular second molar after surgical extraction of mesioangular and horizontal wisdom teeth.Materials & Methods: In this study 26 patient participate for extraction of bilateral mandibular wisdom teeth. Eight cases omitted from study because they were absents for six mounts follow up.1- In test group on one side the defect in distal of the mandibular second molar filled with Neo-Os particles.2- In control group on the other side of the same patient the defect just debridemented.All patients were female at the age between 20-50 years.After six mounts the intra oral radiography and clinical gingival attachment in distal of mandibular second molar were examined for bone regeneration.Results: 1- In this study bone level in the distal of second molar relation to C.E.J in control group 6 months after surgery was upper than the bone level before surgery.2- In this study bone level in the distal of second molar relation to C.E.J in experimental group 6 months after surgery was upper than the bone level before surgery.Conclusion: Statistical analysis (with %95 confidence) shown that there is no difference between test group and control group in bone regeneration.

Introduction: Total hip arthroplasty is one of the most successful procedures for relief of pain and restoration of function in patients with disabling coxarthrosis .complications associated with total hip arthroplasty occur infrequently, but can have a devastating effect on patient outcome.Material & Methods: we prospectively reviewed the records of 106 patients in whom an early post operative and early complications of total hip arthroplasty were done (5day, two and six week).Results: Complications include :1-DVT was the most complication1 5cases (14 percent) 9 woman and 6 man, 2-nerve injury 2 cases (1.8 percent), 3- dislocation 6 cases (5.6 percent), 4-delirium 6cases (5.6 percent), 5-G .I. Bleeding 5 cases (4.7 percent), 6- fracture of femur 6 cases (5.6 percent), 7-acetabular fracture 1 cases (o.9 percent), 8-infection 5 cases (5.6 percent) that 4cases of them were stitch abscess and 1case was severe infectious. Between age, sex, and underline disease with complications there is no significant relationship in this study.Discussion: In this study there is no relation between age, sex, and underline disease, type of operation and causes of operation with complications.

Introduction: BMSCs can become a valuable cell source as an autograft for clinical application involving regeneration of the central nervous system. Recently, multipotential stem cells were identified in adult bone marrow stromal cells; these cells can generate glial and neuronal-like cells with appropriate treatment in culture and can differentiate into neuron-like and glial–like cells. The aim of the present study is to evaluate immunocytochemistry of BMSC which differentiated into neuron-like using deprenyl.Method & Material: Isolated BMSCs from adult rat were passaged for 5 times, and then using cytochemistry and immunofluorescent alkaline phosphatase reaction and fibronectin glycoprotein was assessed. The BMSCs in 5th passage treated with deprenyl after that compared with control group for assessment of BDNF (brain derived neurotrophic factor) expression and tyrosine hydroxylase reaction.Discussion & Conclusion: BMSCs differentiated into neuron– like cells when they are exposed to deprenyl at 10-8 M and expression tyrosine hydroxylase and BDNF. In conclusion, we have demonstrated that in during differentiation BMSCs into dopaminergic neuron which expressed BDNF using deprenyl as inducer.

Background: Recent development has led to introduction of new curing lights (LED, PAC) which are claimed to cure, the composites in shorter time than QTH with the same efficiency.Objective: This study was conducted to compare the curing efficiency of plasma light (Reme Cure, Remedent, USA) and light emitting diode (Free light 3 M, St Paul, MN, USA) with quartz-tungsten-halogen light (Demetron 401, Kerr, Orange, CA, USA).Methods & Materials: Vicker’s micro hardness values on top and bottom surfaces of 1, 2, 3, 4 mm thickness composite cylinders (Filtek Z250 3 M, St Paul, MN, USA) cured in a PTEE mold by irradiation with QTH (40s) and PAC (80) and LED (20s), were measured, and bottom hardness more than 80% to the surface hardness was considered acceptable. Statistical analysis was conducted by utilizing ANOVA at 0.05 significant levels.Result: Significant difference between microvicker’s values in all thicknesses was not found (p>0.05). QTH, LED and PAC curing units created acceptable 3mm depth of curing.

Introduction: Myocardial infarction is one of the most prevalent diseases in most of the countries of the world. Decrease of HDL of serum or increase of LDL of serum increases risk factor, and creates cardiovascular diseases.Material & Methods: In this study, 32 male rats were selected with the same age and weight (200-250gr). They were divided into four groups, each comprising 8 members. The first group was considered as control group and used only ordinary water and food. The second group was addicted and used morphine (1-4 mgr/dl) every day. The third ones, used vitamin E (0.1 mgr/day), in addition to water and food. The fourth one, were addicted and used vitamin E. In practice, morphine sulfate, solved in water and sucrose to become tastier. Vitamin E, was being injected every day in muscle. Blood samples were taken from mice after 30 days, when they were totally dependent on morphine and received sufficient amount of vitamin E.Results: The results showed that, use of morphine in 2nd and 4th groups made an increase of LDL-C in comparison with other groups. The differences were meaningful in p<0.001, Whereas, HDL-C decreased and differences were also meaningful (p<0.01). The amounts of cholesterol in all groups were equal. The amount of triglyceride was remarkably, decreased in rats used Vitamin E in comparison with control group (p<0.001) and as well as the fourth group that had shown a less amount of triglycerides in comparison with the 2nd groups (p<0.01). On the other hand, vitamin E has made an increase the amount of HDL-C/LDL-C ratio, consequently, will increase of risk of occurrence of cardiovascular diseases in addicted persons. However, vitamin E, decreases the ratio of LDL-C/HDL-C and as a result, risk factor is decreased up to 40% in the addicted persons who use vitamin E. Furthermore vitamin E decreases the amount of triglyceride of blood in normal subjects and in addicted ones (25-30%).Conclusion: Therefore, use of vitamin E, which in an antioxidant, in morphine dependant persons, decreases to a great extent, cardiovascular diseases.

Introduction: Candida species have various degrees of susceptibility to antifungal drugs. Thus, detection of antifungal treatment by susceptibility testing methods as a routine test is quit crucial.Materials & Method: A comparison of the disk diffusion method (D.D) as screening test and the reference broth microdilution method (B.M.D) for fluconazole was performed according to national committee for clinical laboratory standards (NCCLS) with106 in one group of Candida spp. in Tehran. Result: In D.D and B.M.D 69.81% and 61.32% of isolates were susceptible(S), whereas 22.6% and 24.52% showed dose-dependent susceptibility (S-DD), and 15.09% and 14.15% were resistant (R), respectively. Susceptibility ranking to fluconazole obtained with all yeasts tested was C.dubliniensis » C.parapsilosis » C.lusittani » C.kefyr > C.albicans > C.tropicalis > C.glabera > C.krusei. Conclusion: C.krusei and C.glaberata showed the highest rate of S-DD/R among all species tested. A total correlation between two methods was measured as 94.34% (p<0.05). The D.D method is recommended as a rapid, simple and reliable screening test for detection of susceptibility and compatible with the gold standard method (B.M.D).

Background: One of the issues which have recently drawn the attention of the experts in the international conferences is the issue of overpopulation. The medical society has offered some effective methods to solve this problem that one method is the sterilizing of women. The most common psychosexual disorders among sterilized women are post-sterilization regret, Loss of libido and fear of feminine. With respect to high risk pregnancy after reversal of tubal ligation as well as inconsistent results of post-sterilization sexual changes, this study designed to investigate post-operation regret rate and sexual changes.Materials & Methods: The study design was descriptive in which 300 sterilized women during 1-5 years ago were selected through cluster randomly sampling. Sterilized women anonymously completed questions about demographic characteristics, post-sterilization regret and sexual changes. Data were collected from the subjects and analyzed by spss11.5 statistics soft ware.Results: Post-sterilization regret reported by 6% of sterilized women which had relation with women's conflict with their husbands concerning decision making before sterilization. Over 75% of 150 study women reported no consistent change in sexual aspects. Among women with consistent change, Negative effects were reported 2 and 5 times more often than positive effects.Conclusion: The results of this research as well as personality and adaptability differences facing the changes revealed that pre-sterilization counseling and post-sterilization follow up system have an important role in women's psychosexual health promotion.

Introduction: Previous findings indicated that glucocorticoids may be affective on modulation of acute and chronic pains.Objective: The present study evaluates interaction between glucocorticoids receptors and opioid system on modulation of acute and chronic pain in mice.Materials and Methods: Male albino mice (25-30 gr. N=150) were used in this experimental study. Formalin test, Tail flick and Hot plate were used for evaluation of analgesic effect of drugs. At the first time we applied subcutaneous injection of vehicle or dexamethasone (0.5 and 1mg/kg) 30 min before the observation test and some groups received naloxone (1mg/kg) simultaneously. Also we used standard criteria for evaluation of pain in three models.Results: Results indicated that dexamethasone have analgesic effect on acute and chronic in three models in comparison to control group (P<0.05), but injection of naloxone modulates of those effects in acute pain and have not significantly effects on chronic pain.The present data provides further evidence for an important role of glucocorticoids on the relief of acute and chronic pain. Also there is interaction between these effects and opioid system.

Introduction: Development of potent anti-tumor drugs with minimum side effects on normal cells is one of the main goals in tumor research field. In this regard natural compounds especially herbal derivatives could be considered as an important source.Objective: In this study, anti-tumor effect of SIM5 -an herbal extract - was studied using two lymphoma tumor cell lines (Raji and Jurkat) in comparison with normal blood mononuclear cells.Materials & Methods: The cells were incubated with various concentrations of SIM5 for 24, 48 and 72 hours and cytotoxic effects were evaluated by MTT test.Results: As the results indicate, tumor cells proliferation and viability was diminished at concentrations between 0.05-1 mg/ml after 24 hours without any significant toxicity on normal mononuclear cells. All concentrations of SIM5 (ranging between 0.01-1 mg/ml) had significant toxic effect on Raji cell line after 48 and 72 hours and 0.05-1 mg/ml of SIM5 had significant toxic effect on Jurkat cell line after 24, 48 and 72 hours. There was no toxic effect on normal mononuclear cells at concentrations less than 1mg/ml of SIM5 after 48 and 72 hours.Conclusion: Further investigation is needed in order to realize the mechanism of effect, optimum dose and the effect of SIM5 in vivo as an anti-tumor drug.