EFFECTS OF KELUSSIA ODORATISSIMA MOZAFFARIAN (KOM) EXTRACT ON BLOOD LIPID IN BALB/C MICE

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SHAHRANI M.; PILEHVARIAN A.A.; KHEYRI SOLEYMAN; ASGARI AZAM; FAROKHI EFAT; PARVIN NEDA; RAFIEIAN MAHMOUD

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Journal: Journal of Shahrekord University of Medical Sciences Year:2009 | Volume:10 | Issue:4 (SUPPL 1 COMPLIMENTARY MEDICINE) Page(s): 50-56

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Title

EFFECTS OF KELUSSIA ODORATISSIMA MOZAFFARIAN (KOM) EXTRACT ON BLOOD LIPID IN BALB/C MICE

Author(s)

Keywords

BLOOD LIPIDQ3

KELUSSIA ODORATISSIMA MOZAFFARIANQ3

MICEQ2

TRIGLYCERIDEQ2

Abstract

Background and aim: Flavonoids constitute a large group of polyphenolic compounds that are found in fruits, vegetables, chocolate, coffee, tea and wine. Consumption of foods rich in flavonoids is associated with a reduced risk of various heart diseases. This experiment was performed to study the antihyperlipidemic effect of KELUSSIA ODORATISSIMA MOZAFFARIAN (KOM) extract in MICE. Methods: 70 Balb/c MICE were divided into 5 groups of 14 animals as follows: group1 (normal diet), group2 (normal diet+olive oil), group3 (high cholesterol diet+olive oil), group 4 (high cholesterol diet+olive oil+10% KOM extract) and group5 (high cholesterol diet+olive oil+20% KOM extract). Lipid profiles (triglyceride, total cholesterol, LDL, HDL and VLDL) and FBS were determined after 2 weeks of extract consumption. The data were analyzed with SPSS software (version 15) and Kruskal-Wallis test. Results: Following two weeks administration of KOM extract on MICE, we found a significant reduction in BLOOD LIPID levels and FBS by using 10% KOM extract (P<0.05). KOM extract (20%) caused a significant reduction in the total cholesterol, LDL and HDL levels and the other factors were not changed (P<0.05). Conclusion: KOM may be beneficial in reduction of lipid profiles.

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APA: Copy

SHAHRANI, M., PILEHVARIAN, A.A., KHEYRI, SOLEYMAN, ASGARI, AZAM, FAROKHI, EFAT, PARVIN, NEDA, & RAFIEIAN, MAHMOUD. (2009). EFFECTS OF KELUSSIA ODORATISSIMA MOZAFFARIAN (KOM) EXTRACT ON BLOOD LIPID IN BALB/C MICE. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, 10(4 (SUPPL 1 COMPLIMENTARY MEDICINE)), 50-56. SID. https://sid.ir/paper/58524/en

Vancouver: Copy

SHAHRANI M., PILEHVARIAN A.A., KHEYRI SOLEYMAN, ASGARI AZAM, FAROKHI EFAT, PARVIN NEDA, RAFIEIAN MAHMOUD. EFFECTS OF KELUSSIA ODORATISSIMA MOZAFFARIAN (KOM) EXTRACT ON BLOOD LIPID IN BALB/C MICE. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2009;10(4 (SUPPL 1 COMPLIMENTARY MEDICINE)):50-56. Available from: https://sid.ir/paper/58524/en

IEEE: Copy

M. SHAHRANI, A.A. PILEHVARIAN, SOLEYMAN KHEYRI, AZAM ASGARI, EFAT FAROKHI, NEDA PARVIN, and MAHMOUD RAFIEIAN, “EFFECTS OF KELUSSIA ODORATISSIMA MOZAFFARIAN (KOM) EXTRACT ON BLOOD LIPID IN BALB/C MICE,” JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, vol. 10, no. 4 (SUPPL 1 COMPLIMENTARY MEDICINE), pp. 50–56, 2009, [Online]. Available: https://sid.ir/paper/58524/en

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