Considering the increase in the world population, human needs for food and energy have been on the increase too. One of the main tasks of the heads in governments is to provide the needed energy for the people in their countries. As the fossil sources are towards their ends and they also are the source of greenhouse gas emissions causing environmental pollution, shifting to renewable sources of energy is an indispensable alternative for most countries. The sun is undoubtedly the most important source of renewable energy. To assess the accessible solar radiation in Mashhad Province from the ordinary meteorological data via Artificial Neural Network (ANN), a survey was conducted. Results indicated that ANN with six variable inputs of: daily mean temperature, daily relative humidity, daily sunshine duration, daily extraterrestrial radiation, number of days of the year and daily dry temperature, with two hidden layers including 37 and 18 neurons respectively, presented a good estimation of a high accuracy for solar radiation. The measured R, MAE, MSE and RMSE were recorded 0.9533, 1.4391, 4.1790, and 2.0443, respectively. Therefore, as for Mashhad, and the regions of similar climate to that of Mashhad, where there is no easy access to solar radiation data, one can use ordinary meteorological data, as above, to estimate the solar radiation with a high degree of acceptable accuracy.