Salinity stress through distractive effects would reduce crop growth and yield. Calcium has nutritional and physiological benefits to crop and therefore, may reduce salinity hazards and cause high growth and yield. In order to study these effects, an experiment with two wheat genotypes G12 (salt tolerant) and G3 (salt sensitive), three levels of salinity (control, 100 and 200 mM NaCl), and three levels of calcium (0.5, 5 and 10 mM CaCl2) was conducted in a hydroponic culture media at the glasshouse of Agricultural Biotechnology Research Institute, Iran. Twenty three days after seeding, salinity treatments gradually were imposed and experiment was continued until physiological maturity. Results showed that in 200 mM NaCl treatment, physiological maturity, plant height, number of tillers per plant, number of spiklets per main spike, number of kernel per main spike, kernel 1000 weight, tillers grain yield, main stem grain yield, biomass and grain yield all were reduced as 31%, 33%, 83%, 36%, 33%,46%, 92%, 68%, 82%, 72%, respectively. Raising calcium concentration in root media reduced salinity effects, so salt tolerance was enhanced. For example, in 200 mM NaCl with 10 mM CaCl2 compared to the same treatment of lacking CaCl2, 1000 kernel weight, total grain yield and biomass in sensitive genotype (G3), were increased by 10%, 14% and 33% respectively. For the tolerant genotype (G12) the corresponding increases were 18%, 33%, and 51%, respectively. Tolerant Genotype (G12) through greater growth ability under salinity stress, produced greater numbers of tillers, main stem grain yield stability, higher kernel weight and led to greater grain yield and biomass as compared to G3.