This study investigated the antecedents and outcomes of goal orientation in a causal model in which student-teacher interaction and self-efficacy were considered as endogenous variables, goal orientation as the mediating variable and academic buoyancy as the exogenous variable. Participants were 516 high school students (291 boys and 225 girls) in Kazeroun who completed Academic Buoyancy Questionnaire (Hosseinchari & Dehghani, 1391), Goal Orientation Scale (Elliot & Mcgregor, 2001), Teacher-Students Interaction Questionnaire (Wubbles, Creton, Levy & Hooymayer, 1993), and Self-efficacy Scale (Moris, 2001). Descriptive statistical methods and path analysis were used to test the model. Results revealed that emotional and social self-efficacy dimensions of self-efficacy predicted academic buoyancy both directly and indirectly, through mastery approach goal orientation. However, academic self-efficacy only predicted academic buoyancy through mastery approach goal orientation. None of the teacher-student interaction dimensions predicted academic buoyancy directly. Mastery-avoidance goal orientation mediated the relationship between control and orientation dimensions of teacher-student interaction and academic buoyancy. After all, the research findings contributed theoretical knowledge, academic buoyancy and provide some for implications promoting students’ academic buoyancy skill more implications and justificationson of the results discussed in the final chapter.